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pubmed-article:10785799pubmed:abstractTextReaction of the ethyl 3-arylpyruvate 5a with the methyl 2-bromo-3-arylpyruvate 6b in the presence of the 2-arylethylamine 4 afforded the pyrrole derivative 10, which could be transformed into lamellarin L (1) in five steps. The synthesis proceeds with 38% overall yield and mimics the probable biosynthesis of these marine alkaloids.lld:pubmed
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pubmed-article:10785799pubmed:dateRevised2009-8-4lld:pubmed
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pubmed-article:10785799pubmed:articleTitleAlkaloids from marine organisms, Part 5. Biomimetic total synthesis of lamellarin L by coupling of two different arylpyruvic acid units.lld:pubmed
pubmed-article:10785799pubmed:affiliationC. Winklhofer Institut für Organische Chemie, Universität München, Germany.lld:pubmed
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pubmed-article:10785799pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed