Recent evidence shows that 15(S)-hydroxy-eicoisatetraenoic acid (15[S]-HETE) can be released and rapidly reincorporated into cellular lipids. These mechanisms exert several immunoregulatory functions that may be relevant in airway inflammation.
Istituto di Fisiopatologia Respiratoria, Consiglio delle Ricerche, and the Istituto di Medicina Generale e Pneumologia, University of Palermo, Palermo, Italy.