| pubmed-article:10736327 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0020291 | lld:lifeskim |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0023401 | lld:lifeskim |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0041942 | lld:lifeskim |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0030011 | lld:lifeskim |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0489617 | lld:lifeskim |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:10736327 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
| pubmed-article:10736327 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:10736327 | pubmed:dateCreated | 2000-4-24 | lld:pubmed |
| pubmed-article:10736327 | pubmed:abstractText | The quantitative relationships between nitrogen (N) intake, urea production, excretion and amino acid oxidation are currently a matter of debate. Some investigators have proposed that urea production is essentially constant over a wide range of N intakes and that urea hydrolysis is regulated according to the N needs of the organism. We have assessed this proposal by compiling results from four separate experiments in healthy young adults (n = 34) carried out in our laboratories and all at the end of the respective diet periods using an identical 24-h continuous intravenous infusion of [(15)N, (15)N]urea and L-[1-(13)C]leucine. The N intakes were: expt. 1; protein-free diet for 5 d; expt. 2; N at 44 mg N. kg(-1). d(-1) from a balanced L-amino acid mixture for 13 d; expt. 3; N at 161 mg. kg(-1). d(-1) from egg protein for 6 d; expt. 4 -one group received 157 mg. kg(-1). d(-1) and the other 392 mg. kg(-1). d(-1) from milk-protein-based diets for 6 d. Urea production and excretion were linearly correlated with N intake (r = 0.98 and 0.94, respectively; P < 0.01). Urea hydrolysis increased linearly with N intake (r = 0.7; P < 0.05), with considerable variation in the rate among individuals, especially at the N intake of approximately 160 mg N. kg(-1)d(-1). These findings are consistent with the generally accepted view that a control of body N balance is via a regulation of urea production. They do not support the concept that urea hydrolysis is the more important site in the control of body N loss. | lld:pubmed |
| pubmed-article:10736327 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10736327 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10736327 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10736327 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10736327 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10736327 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10736327 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10736327 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10736327 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:10736327 | pubmed:issn | 0022-3166 | lld:pubmed |
| pubmed-article:10736327 | pubmed:author | pubmed-author:YoungV RVR | lld:pubmed |
| pubmed-article:10736327 | pubmed:author | pubmed-author:HambraeusLL | lld:pubmed |
| pubmed-article:10736327 | pubmed:author | pubmed-author:RagusoC ACA | lld:pubmed |
| pubmed-article:10736327 | pubmed:author | pubmed-author:El-KhouryA... | lld:pubmed |
| pubmed-article:10736327 | pubmed:author | pubmed-author:ForslundA HAH | lld:pubmed |
| pubmed-article:10736327 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10736327 | pubmed:volume | 130 | lld:pubmed |
| pubmed-article:10736327 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10736327 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10736327 | pubmed:pagination | 761-6 | lld:pubmed |
| pubmed-article:10736327 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:meshHeading | pubmed-meshheading:10736327... | lld:pubmed |
| pubmed-article:10736327 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10736327 | pubmed:articleTitle | Rates of urea production and hydrolysis and leucine oxidation change linearly over widely varying protein intakes in healthy adults. | lld:pubmed |
| pubmed-article:10736327 | pubmed:affiliation | Laboratory of Human Nutrition and Clinical Research Center Massachusetts Institute of Technology, Cambridge, MA 02139, USA. | lld:pubmed |
| pubmed-article:10736327 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10736327 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10736327 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10736327 | lld:pubmed |
