| pubmed-article:10721633 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C0035804 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C1527390 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C1868671 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C0015205 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C0024485 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C1579762 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C0009491 | lld:lifeskim |
| pubmed-article:10721633 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:10721633 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:10721633 | pubmed:dateCreated | 2000-4-11 | lld:pubmed |
| pubmed-article:10721633 | pubmed:abstractText | The measurement of tumor volumes is a practical and objective method of assessing the efficacy of a therapeutic agent. However, the relative accuracy of different methods of assessing tumor volume has been unclear. Using T1-weighted, gadolinium-enhanced magnetic resonance Imaging (T1-MRI), Evans Blue infusion and histology we measured intracranial tumor volumes in a rodent brain tumor model (RT2) at days 10, 16 and 18 after implantation of cells in the caudate putamen. There is a good correlation between tumor volumes comparing T1-MRI and Evans Blue (r2 = 0.99), T1-MRI and Histology (r2 = 0.98) and histology and Evans Blue (r2 = 0.93). Each of these methods is reliable in estimating tumor volumes in laboratory animals. There was significant uptake of gadolinium and Evans Blue in the tumor suggesting a wide disruption of the blood-brain barrier. | lld:pubmed |
| pubmed-article:10721633 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10721633 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10721633 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10721633 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10721633 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10721633 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10721633 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10721633 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10721633 | pubmed:issn | 0018-9294 | lld:pubmed |
| pubmed-article:10721633 | pubmed:author | pubmed-author:PrabhuS SSS | lld:pubmed |
| pubmed-article:10721633 | pubmed:author | pubmed-author:GilliesG TGT | lld:pubmed |
| pubmed-article:10721633 | pubmed:author | pubmed-author:ALHAAA | lld:pubmed |
| pubmed-article:10721633 | pubmed:author | pubmed-author:BroaddusW CWC | lld:pubmed |
| pubmed-article:10721633 | pubmed:author | pubmed-author:OveissiCC | lld:pubmed |
| pubmed-article:10721633 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10721633 | pubmed:volume | 47 | lld:pubmed |
| pubmed-article:10721633 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10721633 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10721633 | pubmed:pagination | 259-65 | lld:pubmed |
| pubmed-article:10721633 | pubmed:dateRevised | 2009-11-11 | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:meshHeading | pubmed-meshheading:10721633... | lld:pubmed |
| pubmed-article:10721633 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10721633 | pubmed:articleTitle | Determination of intracranial tumor volumes in a rodent brain using magnetic resonance imaging, Evans blue, and histology: a comparative study. | lld:pubmed |
| pubmed-article:10721633 | pubmed:affiliation | Division of Neurosurgery, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298, USA. | lld:pubmed |
| pubmed-article:10721633 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10721633 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10721633 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10721633 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
