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pubmed-article:10694607pubmed:abstractTextThe perfect strategy for pulmonary graft preservation remains elusive. Experimental work supports the use of perfusates, such as Euro-Collins, University of Wisconsin, and low-potassium dextran solutions. We use low-potassium dextran solution in our clinical program, but we aim for continued improvement. The trisaccharide raffinose has been shown to be responsible for the efficacy of University of Wisconsin perfusate in lung preservation. Raffinose is superior to a variety of other saccharides for this purpose. We tested the hypothesis that the addition of raffinose to low-potassium dextran solution might further improve graft function.lld:pubmed
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pubmed-article:10694607pubmed:authorpubmed-author:KeshavjeeSSlld:pubmed
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pubmed-article:10694607pubmed:pagination488-92lld:pubmed
pubmed-article:10694607pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:10694607pubmed:articleTitleRaffinose improves the function of rat pulmonary grafts stored for twenty-four hours in low-potassium dextran solution.lld:pubmed
pubmed-article:10694607pubmed:affiliationThoracic Surgery Research Laboratory, Division of Thoracic Surgery, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.lld:pubmed
pubmed-article:10694607pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10694607pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed