| pubmed-article:10694580 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10694580 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:10694580 | lifeskim:mentions | umls-concept:C0022688 | lld:lifeskim |
| pubmed-article:10694580 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:10694580 | lifeskim:mentions | umls-concept:C2709199 | lld:lifeskim |
| pubmed-article:10694580 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:10694580 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:10694580 | pubmed:dateCreated | 2000-4-25 | lld:pubmed |
| pubmed-article:10694580 | pubmed:abstractText | Studies of natural killer (NK) cell function in vivo have been challenging primarily due to the lack of animal models in which NK cells are genetically and selectively deficient. Here, we describe a transgenic mouse with defective natural killing and selective deficiency in NK1.1(+) CD3(-) cells. Despite functionally normal B, T, and NK/T cells, transgenic mice displayed impaired acute in vivo rejection of tumor cells. Adoptive transfer experiments confirmed that NK1.1(+) CD3(-) cells were responsible for acute tumor rejection, establishing the relationship of NK1.1(+) CD3(-) cells to NK cells. Additional studies provided evidence that (i) NK cells play an important role in suppressing tumor metastasis and outgrowth; (ii) NK cells are major producers of IFNgamma in response to bacterial endotoxin but not to interleukin-12, and; (iii) NK cells are not essential for humoral responses to T cell-independent type 2 antigen or the generalized Shwartzman reaction, both of which were previously proposed to involve NK cells. | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10694580 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10694580 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10694580 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10694580 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:10694580 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:10694580 | pubmed:author | pubmed-author:KimSS | lld:pubmed |
| pubmed-article:10694580 | pubmed:author | pubmed-author:WeissmanI LIL | lld:pubmed |
| pubmed-article:10694580 | pubmed:author | pubmed-author:IizukaKK | lld:pubmed |
| pubmed-article:10694580 | pubmed:author | pubmed-author:YokoyamaW MWM | lld:pubmed |
| pubmed-article:10694580 | pubmed:author | pubmed-author:AguilaH LHL | lld:pubmed |
| pubmed-article:10694580 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10694580 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:10694580 | pubmed:volume | 97 | lld:pubmed |
| pubmed-article:10694580 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10694580 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10694580 | pubmed:pagination | 2731-6 | lld:pubmed |
| pubmed-article:10694580 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:meshHeading | pubmed-meshheading:10694580... | lld:pubmed |
| pubmed-article:10694580 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10694580 | pubmed:articleTitle | In vivo natural killer cell activities revealed by natural killer cell-deficient mice. | lld:pubmed |
| pubmed-article:10694580 | pubmed:affiliation | Howard Hughes Medical Institute, Rheumatology Division, Box 8045, Washington University School of Medicine, St. Louis, MO 63110, USA. | lld:pubmed |
| pubmed-article:10694580 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10694580 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10694580 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:11909 | entrezgene:pubmed | pubmed-article:10694580 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10694580 | lld:pubmed |
