Phosphorylation of recombinant human ATP:citrate lyase by cAMP-dependent protein kinase abolishes homotropic allosteric regulation of the enzyme by citrate and increases the enzyme activity. Allosteric activation of ATP:citrate lyase by phosphorylated sugars.

Source:http://linkedlifedata.com/resource/pubmed/id/10653665

Biochemistry 2000 Feb 8 39 5 1169-79

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10653665