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pubmed-article:10632995pubmed:abstractTextWe researched epidemiologic associations between environmental and demographic factors and prevalence of Helicobacter pylori infection in a suburban Jamaican community. Using a clustered sampling technique, 22 domestic yards enclosing 60 separate households were randomly selected from a local community. All household members (n = 346) were invited to participate following informed consent; the overall compliance rate was 58.9%. A commercial enzyme immunoassay (HMáCAP) was used to detect IgG antibodies raised against H. pylori. Environmental and demographic information was obtained by questionnaire. The seroprevalence of H. pylori was 69.9% (n = 202). Analysis of the independent variables revealed three major components: Component 1 described, collectively, good personal hygiene and sanitation, indoor water supply and absence of straying animals in the peridomestic area; Component 2 included older age, good personal hygiene and large yard size; Component 3 the presence of domestic animals (cats and dogs) and, again, large yard size. These three complexes explained 42.2% of the variability in the data set. Logistic regression showed that Components 2 and 3 were independently associated with H. pylori seropositivity, indicating that a combination of demographic, environmental and zoonotic factors is involved in the spread of H. pylori infections at the tropical community level.lld:pubmed
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pubmed-article:10632995pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:10632995pubmed:articleTitleSeroepidemiology of Helicobacter pylori infection in a Jamaican community.lld:pubmed
pubmed-article:10632995pubmed:affiliationDepartment of Microbiology, The University of West Indies, Kingston, Jamaica.lld:pubmed
pubmed-article:10632995pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10632995pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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