| pubmed-article:10624701 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10624701 | lifeskim:mentions | umls-concept:C0025266 | lld:lifeskim |
| pubmed-article:10624701 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:10624701 | lifeskim:mentions | umls-concept:C0002844 | lld:lifeskim |
| pubmed-article:10624701 | lifeskim:mentions | umls-concept:C0014939 | lld:lifeskim |
| pubmed-article:10624701 | lifeskim:mentions | umls-concept:C0969677 | lld:lifeskim |
| pubmed-article:10624701 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:10624701 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10624701 | pubmed:dateCreated | 2000-2-3 | lld:pubmed |
| pubmed-article:10624701 | pubmed:abstractText | There is evidence supporting a role for sex hormones in the etiology of prostate cancer. Supplementation with alpha-tocopherol reduced prostate cancer in the alpha-Tocopherol, beta-Carotene Prevention Study (ATBC Study). The objective of this study was to assess the relation of baseline levels of serum alpha-tocopherol and serum sex hormones in older men. A cross-sectional analysis of serum alpha-tocopherol and sex hormone concentrations was conducted within a subset of the ATBC Study. Serum was collected in the morning after an overnight fast at baseline from 204 men ages 50-69 years participating in the ATBC Study and free of prostate cancer. Hormones were measured by radioimmunoassay, and alpha-tocopherol was measured by high-performance liquid chromatography by standard procedures. Multivariate linear regression was used to evaluate the association of serum alpha-tocopherol with nine androgens and estrogens after controlling for age, body mass index, hormone assay batch, and serum cholesterol. Serum alpha-tocopherol was significantly inversely associated with serum androstenedione, testosterone, sex hormone-binding globulin, and estrone. The difference in hormone concentration per milligram of alpha-tocopherol was 1.8-2.6% for these four hormones. These results indicated that alpha-tocopherol is related to concentrations of several sex hormones in older men and may have implications for the observed protective effect of supplemental vitamin E in relation to prostate cancer in the ATBC Study. | lld:pubmed |
| pubmed-article:10624701 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10624701 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10624701 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10624701 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10624701 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10624701 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10624701 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10624701 | pubmed:issn | 0163-5581 | lld:pubmed |
| pubmed-article:10624701 | pubmed:author | pubmed-author:VirtamoJJ | lld:pubmed |
| pubmed-article:10624701 | pubmed:author | pubmed-author:TaylorP RPR | lld:pubmed |
| pubmed-article:10624701 | pubmed:author | pubmed-author:TangreaJ AJA | lld:pubmed |
| pubmed-article:10624701 | pubmed:author | pubmed-author:AlbanesDD | lld:pubmed |
| pubmed-article:10624701 | pubmed:author | pubmed-author:HartmanT JTJ | lld:pubmed |
| pubmed-article:10624701 | pubmed:author | pubmed-author:DorganJ FJF | lld:pubmed |
| pubmed-article:10624701 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10624701 | pubmed:volume | 35 | lld:pubmed |
| pubmed-article:10624701 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10624701 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10624701 | pubmed:pagination | 10-5 | lld:pubmed |
| pubmed-article:10624701 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:meshHeading | pubmed-meshheading:10624701... | lld:pubmed |
| pubmed-article:10624701 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10624701 | pubmed:articleTitle | Association between serum alpha-tocopherol and serum androgens and estrogens in older men. | lld:pubmed |
| pubmed-article:10624701 | pubmed:affiliation | Division of Clinical Sciences, National Cancer Institute, Bethesda, MD 20892, USA. th86d@nih.gov | lld:pubmed |
| pubmed-article:10624701 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10624701 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
