Linked Life Data

10623799

Source:http://linkedlifedata.com/resource/pubmed/id/10623799

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:10623799rdf:typepubmed:Citationlld:pubmed
pubmed-article:10623799lifeskim:mentionsumls-concept:C0086418lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0007634lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0021758lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0214743lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0205147lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0020846lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C1704675lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C1291802lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0030685lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0162825lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0680255lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0205263lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C0391871lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C1283071lld:lifeskim
pubmed-article:10623799lifeskim:mentionsumls-concept:C1963578lld:lifeskim
pubmed-article:10623799pubmed:issue2lld:pubmed
pubmed-article:10623799pubmed:dateCreated2000-2-10lld:pubmed
pubmed-article:10623799pubmed:abstractTextHIV-1 glycoprotein (gp) 120 from different clades is a potent stimulus for IL-4 and IL-13 release from basophils purified from healthy individuals seronegative for Abs to HIV-1 and HIV-2. IL-4 mRNA, constitutively present in basophils, was increased after stimulation by gp120 and was inhibited cyclosporin A and tacrolimus. IL-4 and IL-13 secretion from basophils activated by gp120 was not correlated. There was a correlation between the maximum gp120- and anti-IgE-induced IL-4 release from basophils. The average t1/2 gp120-induced IL-4 release was lower than for IL-13 release. Basophils from which IgE had been dissociated by brief exposure to lactic acid no longer released IL-4 in response to gp120 or to anti-IgE. The response to a mAb cross-linking the alpha-chain of high-affinity receptor for IgE (Fc epsilon RI) was unaffected by this treatment. Three human VH3+ monoclonal IgM inhibited gp120-induced secretion of IL-4 from basophils. In contrast, VH6+ monoclonal IgM did not inhibit the release of IL-4 induced by gp120. Synthetic peptides distant from the NH2 and COOH termini of gp120MN inhibited the activating property of gp120MN. These results indicate that gp120, which acts as a viral superantigen, interacts with the VH3 region of IgE to induce the release of IL-4 and IL-13 from human Fc epsilon RI+ cells.lld:pubmed
pubmed-article:10623799pubmed:languageenglld:pubmed
pubmed-article:10623799pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:citationSubsetAIMlld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10623799pubmed:statusMEDLINElld:pubmed
pubmed-article:10623799pubmed:monthJanlld:pubmed
pubmed-article:10623799pubmed:issn0022-1767lld:pubmed
pubmed-article:10623799pubmed:authorpubmed-author:MaroneGGlld:pubmed
pubmed-article:10623799pubmed:authorpubmed-author:FlorioGGlld:pubmed
pubmed-article:10623799pubmed:authorpubmed-author:PatellaVVlld:pubmed
pubmed-article:10623799pubmed:authorpubmed-author:PetraroliAAlld:pubmed
pubmed-article:10623799pubmed:issnTypePrintlld:pubmed
pubmed-article:10623799pubmed:day15lld:pubmed
pubmed-article:10623799pubmed:volume164lld:pubmed
pubmed-article:10623799pubmed:ownerNLMlld:pubmed
pubmed-article:10623799pubmed:authorsCompleteYlld:pubmed
pubmed-article:10623799pubmed:pagination589-95lld:pubmed
pubmed-article:10623799pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:meshHeadingpubmed-meshheading:10623799...lld:pubmed
pubmed-article:10623799pubmed:year2000lld:pubmed
pubmed-article:10623799pubmed:articleTitleHIV-1 gp120 induces IL-4 and IL-13 release from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE.lld:pubmed
pubmed-article:10623799pubmed:affiliationUniversity of Naples Federico II, Division of Clinical Immunology and Allergy, Naples, Italy.lld:pubmed
pubmed-article:10623799pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10623799pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:3565entrezgene:pubmedpubmed-article:10623799lld:entrezgene
entrez-gene:3596entrezgene:pubmedpubmed-article:10623799lld:entrezgene
entrez-gene:155971entrezgene:pubmedpubmed-article:10623799lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10623799lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10623799lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10623799lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:10623799lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10623799lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10623799lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10623799lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10623799lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10623799lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10623799lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10623799lld:pubmed