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pubmed-article:10620566pubmed:abstractTextDihydropyrimidine dehydrogenase (DPD) catalyzes the degradation of thymine, uracil, and the chemotherapeutic drug 5-fluorouracil. To identify patients suffering from complete or partial DPD deficiency and to identify pitfalls that can preclude the proper diagnosis of patients with partial DPD deficiency, a sensitive and accurate assay is necessary.lld:pubmed
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pubmed-article:10620566pubmed:articleTitlePitfalls in the diagnosis of patients with a partial dihydropyrimidine dehydrogenase deficiency.lld:pubmed
pubmed-article:10620566pubmed:affiliationLaboratory Genetic Metabolic Diseases, F0-224, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. a.b.vanKuilenburg@amc.uva.nllld:pubmed
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