| pubmed-article:10617463 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10617463 | lifeskim:mentions | umls-concept:C0026609 | lld:lifeskim |
| pubmed-article:10617463 | lifeskim:mentions | umls-concept:C0162638 | lld:lifeskim |
| pubmed-article:10617463 | lifeskim:mentions | umls-concept:C0038838 | lld:lifeskim |
| pubmed-article:10617463 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:10617463 | pubmed:issue | 5449 | lld:pubmed |
| pubmed-article:10617463 | pubmed:dateCreated | 2000-1-11 | lld:pubmed |
| pubmed-article:10617463 | pubmed:abstractText | Mutations in copper, zinc superoxide dismutase (SOD) have been implicated in the selective death of motor neurons in 2 percent of amyotrophic lateral sclerosis (ALS) patients. The loss of zinc from either wild-type or ALS-mutant SODs was sufficient to induce apoptosis in cultured motor neurons. Toxicity required that copper be bound to SOD and depended on endogenous production of nitric oxide. When replete with zinc, neither ALS-mutant nor wild-type copper, zinc SODs were toxic, and both protected motor neurons from trophic factor withdrawal. Thus, zinc-deficient SOD may participate in both sporadic and familial ALS by an oxidative mechanism involving nitric oxide. | lld:pubmed |
| pubmed-article:10617463 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10617463 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10617463 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10617463 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:10617463 | pubmed:issn | 0036-8075 | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:TarpeyM MMM | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:BeckmanJ SJS | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:SampsonJ BJB | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:ZhuangYY | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:BarbeitoLL | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:ReiterCC | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:EstévezA GAG | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:CrowJ PJP | lld:pubmed |
| pubmed-article:10617463 | pubmed:author | pubmed-author:RichardsonG... | lld:pubmed |
| pubmed-article:10617463 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10617463 | pubmed:day | 24 | lld:pubmed |
| pubmed-article:10617463 | pubmed:volume | 286 | lld:pubmed |
| pubmed-article:10617463 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10617463 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10617463 | pubmed:pagination | 2498-500 | lld:pubmed |
| pubmed-article:10617463 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:meshHeading | pubmed-meshheading:10617463... | lld:pubmed |
| pubmed-article:10617463 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10617463 | pubmed:articleTitle | Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. | lld:pubmed |
| pubmed-article:10617463 | pubmed:affiliation | Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, AL 35233, USA. | lld:pubmed |
| pubmed-article:10617463 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10617463 | pubmed:publicationType | Comment | lld:pubmed |
| pubmed-article:10617463 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10617463 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10617463 | lld:pubmed |
