| pubmed-article:10611367 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10611367 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:10611367 | lifeskim:mentions | umls-concept:C0006685 | lld:lifeskim |
| pubmed-article:10611367 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:10611367 | pubmed:issue | 26 | lld:pubmed |
| pubmed-article:10611367 | pubmed:dateCreated | 2000-1-27 | lld:pubmed |
| pubmed-article:10611367 | pubmed:abstractText | The L type calcium channel agonist (+/-)Bay K 8644 has been reported to cause characteristic motor abnormalities in adult mice. The current study shows that administration of this drug can also cause the unusual phenomenon of self-injurious biting, particularly when given to young mice. Self-biting is provoked by injecting small quantities of (+/-)Bay K 8644 directly into the lateral ventricle of the brain, suggesting a central effect of the drug. Similar behaviors can be provoked by administration of another L type calcium channel agonist, FPL 64176. The self-biting provoked by (+/-)Bay K 8644 can be inhibited by pretreating the mice with dihydropyridine L type calcium channel antagonists such as nifedipine, nimodipine, or nitrendipine. However, self-biting is not inhibited by nondihydropyridine antagonists including diltiazem, flunarizine, or verapamil. The known actions of (+/-)Bay K 8644 as an L type calcium channel agonist, the reproduction of similar behavior with another L type calcium channel agonist, and the protection afforded by certain L type calcium channel antagonists implicate calcium channels in the mediation of the self-biting behavior. This phenomenon provides a model for studying the neurobiology of this unusual behavior. | lld:pubmed |
| pubmed-article:10611367 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10611367 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10611367 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10611367 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:10611367 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:10611367 | pubmed:author | pubmed-author:KimB SBS | lld:pubmed |
| pubmed-article:10611367 | pubmed:author | pubmed-author:FordL CLC | lld:pubmed |
| pubmed-article:10611367 | pubmed:author | pubmed-author:RothsteinJ... | lld:pubmed |
| pubmed-article:10611367 | pubmed:author | pubmed-author:JinnahH AHA | lld:pubmed |
| pubmed-article:10611367 | pubmed:author | pubmed-author:YittaSS | lld:pubmed |
| pubmed-article:10611367 | pubmed:author | pubmed-author:VisserJ EJE | lld:pubmed |
| pubmed-article:10611367 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10611367 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:10611367 | pubmed:volume | 96 | lld:pubmed |
| pubmed-article:10611367 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10611367 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10611367 | pubmed:pagination | 15228-32 | lld:pubmed |
| pubmed-article:10611367 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:meshHeading | pubmed-meshheading:10611367... | lld:pubmed |
| pubmed-article:10611367 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10611367 | pubmed:articleTitle | Calcium channel activation and self-biting in mice. | lld:pubmed |
| pubmed-article:10611367 | pubmed:affiliation | Department of Neurology, Johns Hopkins Hospital, Baltimore, MD 21287, USA. hjinnah@welch.jhu.edu | lld:pubmed |
| pubmed-article:10611367 | pubmed:publicationType | Journal Article | lld:pubmed |
