| pubmed-article:10606979 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C0024141 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C0125090 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C1749467 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C0205177 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:10606979 | lifeskim:mentions | umls-concept:C1335808 | lld:lifeskim |
| pubmed-article:10606979 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10606979 | pubmed:dateCreated | 2000-2-7 | lld:pubmed |
| pubmed-article:10606979 | pubmed:abstractText | The adhesion molecule L-selectin (CD62L) mediates lymphocyte recirculation and leucocyte rolling on vascular endothelium at sites of inflammation. Serum levels of soluble L-selectin (sL-selectin) were measured in patients with SLE in order to relate these levels to clinical activity and immunological parameters. An ELISA was used to detect the soluble form of human L-selectin (CD62L) in 42 patients with SLE and in 33 healthy individuals. The mean +/- s.e.m. values of sL-selectin were 1285 +/- 121 ng/ml for patients with SLE and 986 +/- 180 ng/ml for healthy blood donors, but there was no significant difference. When patients with active SLE were analysed, higher levels of circulating sL-selectin were found when compared with patients without activity (1497 +/- 167 ng/ml versus 941 +/- 150 ng/ml; P = 0.028). We found a significant correlation between the levels of sL-selectin and of dsDNA antibodies (r = 0.36, P = 0. 044) and between levels of sL-selectin and SLE Disease Activity Index (SLEDAI) score (r = 0.42, P = 0.003). Patients with active SLE studied cross-sectionally showed significant elevations of sL-selectin (CD62L) compared with controls. Thus, the levels of this soluble adhesion molecule correlated with active disease and levels of anti-dsDNA antibodies. | lld:pubmed |
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| pubmed-article:10606979 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10606979 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10606979 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10606979 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10606979 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10606979 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10606979 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:10606979 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:EngelPP | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:FontJJ | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:NavarroMM | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:IngelmoMM | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:CerveraRR | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:PizcuetaPP | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:García-Carras... | lld:pubmed |
| pubmed-article:10606979 | pubmed:author | pubmed-author:Ramos-CasalsM... | lld:pubmed |
| pubmed-article:10606979 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10606979 | pubmed:volume | 119 | lld:pubmed |
| pubmed-article:10606979 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10606979 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10606979 | pubmed:pagination | 169-74 | lld:pubmed |
| pubmed-article:10606979 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:10606979 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10606979 | pubmed:articleTitle | Increased serum levels of soluble L-selectin (CD62L) in patients with active systemic lupus erythematosus (SLE). | lld:pubmed |
| pubmed-article:10606979 | pubmed:affiliation | Systemic Autoimmune Diseases Unit, Department of Cellular Biology, University of Barcelona, Spain. font@medicina.ub.es | lld:pubmed |
| pubmed-article:10606979 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10606979 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10606979 | lld:pubmed |
