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pubmed-article:10606381pubmed:abstractTextFibromyalgia (FM) and chronic fatigue syndrome (CFS) are stress associated disorders mainly affecting women. FM is characterized primarily by widespread musculoskeletal pain, and CFS by profound debilitating fatigue, but there is considerable overlap of clinical symptoms between these 2 syndromes. Neuroendocrine abnormalities have been noted in both FM and CFS and desynchronization of circadian systems has been postulated in their etiology. The pineal hormone melatonin is involved in synchronizing circadian systems and the use of exogenous melatonin has become widespread in patients with FM and CFS.lld:pubmed
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pubmed-article:10606381pubmed:articleTitleMelatonin levels in women with fibromyalgia and chronic fatigue syndrome.lld:pubmed
pubmed-article:10606381pubmed:affiliationDepartment of Psychiatry, University of Michigan Medical Center, Ann Arbor, USA. akorszun@umich.edulld:pubmed
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