| pubmed-article:10594560 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10594560 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:10594560 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:10594560 | lifeskim:mentions | umls-concept:C0441994 | lld:lifeskim |
| pubmed-article:10594560 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:10594560 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
| pubmed-article:10594560 | lifeskim:mentions | umls-concept:C2610891 | lld:lifeskim |
| pubmed-article:10594560 | lifeskim:mentions | umls-concept:C0887947 | lld:lifeskim |
| pubmed-article:10594560 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10594560 | pubmed:dateCreated | 2000-1-13 | lld:pubmed |
| pubmed-article:10594560 | pubmed:abstractText | HAART may increase CD4+ T cell counts despite a persistently detectable HIV load. The impact of HAART on apoptosis, which may play a role in the disease process in HIV-infected patients, has not been extensively studied. We performed a study to compare the level of spontaneous T cell apoptosis and anti-retroviral treatments in a cohort of HIV-1-infected patients. Data were obtained from a computerized medical record. Quantification of apoptotic cells was by cytofluorometric technique. From November 1995 to December 1997 we studied T cell apoptosis in 112 HIV-infected patients. Forty patients were classified A, 36 B and 36 C. Thirty patients were naive and 82 received an anti-retroviral treatment, 49 including a protease inhibitor (PI). The median plasma viraemia determined in 63 patients was 3.6 (range 1.3-5.6) log10. The median apoptotic cell count was 22% (range 2-73%) and 12% (range 2-60%) for CD4+ and CD8+ T cells, respectively. We did not observe any correlation between the HIV viraemia and the level of apoptosis of T cell subsets. Patients with HAART showed a lower percentage of apoptotic CD4+ T cells only: 16% (range 2-61%) versus 25% (range 5-73%) for patients receiving two nucleoside analogues (P = 0.02). This effect was significant in stage A patients and remained observable during the whole course of HIV disease. In conclusion, HAART, without any relation to plasma viraemia, is able to reduce apoptosis of CD4+ T cells. | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10594560 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10594560 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10594560 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10594560 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:10594560 | pubmed:issn | 0009-9104 | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:BernardAA | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:DellamonicaPP | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:ArlottiMM | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:BreittmayerJ... | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:PugliesePP | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:PradierCC | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:Bernard-Pomie... | lld:pubmed |
| pubmed-article:10594560 | pubmed:author | pubmed-author:RogerP MPM | lld:pubmed |
| pubmed-article:10594560 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10594560 | pubmed:volume | 118 | lld:pubmed |
| pubmed-article:10594560 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10594560 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10594560 | pubmed:pagination | 412-6 | lld:pubmed |
| pubmed-article:10594560 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:meshHeading | pubmed-meshheading:10594560... | lld:pubmed |
| pubmed-article:10594560 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10594560 | pubmed:articleTitle | Highly active anti-retroviral therapy (HAART) is associated with a lower level of CD4+ T cell apoptosis in HIV-infected patients. | lld:pubmed |
| pubmed-article:10594560 | pubmed:affiliation | Service des Maladies Infectieuses et Tropicales, INSERM U343, Hôpital de l'Archet, Nice, France. | lld:pubmed |
| pubmed-article:10594560 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10594560 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10594560 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10594560 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10594560 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10594560 | lld:pubmed |
