| pubmed-article:10581483 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10581483 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:10581483 | lifeskim:mentions | umls-concept:C0041341 | lld:lifeskim |
| pubmed-article:10581483 | lifeskim:mentions | umls-concept:C0679466 | lld:lifeskim |
| pubmed-article:10581483 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:10581483 | pubmed:dateCreated | 2000-2-24 | lld:pubmed |
| pubmed-article:10581483 | pubmed:abstractText | Webb, Thomson, and Osborne [1991: Arch Dis Child 66:1375-1377] reported on the pattern of cerebral lesions found in an epidemiological sample of patients with tuberous sclerosis (TS) and clinically judged to be of normal intellect. Varying numbers of tubers and subependymal nodules were found, but clinically there appeared to be few associated neuropsychological impairments. Our objectives in this study were to conduct a detailed neuropsychological assessment to determine whether these patients were indeed free of cognitive deficits. We report the results of a detailed neuropsychological assessment in this sample and a matched comparison group. Although of average intelligence, most TS individuals had a significant cognitive deficit of one sort or another, and in a number of cases the pattern of cognitive impairments matched that seen in other neurological disorders. Additionally, the overall rate of cognitive deficits was significantly greater than in the controls. We conclude that normally intelligent individuals with TS are prone to specific cognitive difficulties. Further research will be required to clarify the nature of the links between the brain abnormalities and type of neuropsychological dysfunction. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:642-646, 1999. | lld:pubmed |
| pubmed-article:10581483 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10581483 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10581483 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10581483 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10581483 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:10581483 | pubmed:issn | 0148-7299 | lld:pubmed |
| pubmed-article:10581483 | pubmed:author | pubmed-author:HarrisonJ EJE | lld:pubmed |
| pubmed-article:10581483 | pubmed:author | pubmed-author:HancockEE | lld:pubmed |
| pubmed-article:10581483 | pubmed:author | pubmed-author:OsborneJ PJP | lld:pubmed |
| pubmed-article:10581483 | pubmed:author | pubmed-author:BoltonP FPF | lld:pubmed |
| pubmed-article:10581483 | pubmed:author | pubmed-author:O'CallaghanF... | lld:pubmed |
| pubmed-article:10581483 | pubmed:copyrightInfo | Copyright 1999 Wiley-Liss, Inc. | lld:pubmed |
| pubmed-article:10581483 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10581483 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:10581483 | pubmed:volume | 88 | lld:pubmed |
| pubmed-article:10581483 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10581483 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10581483 | pubmed:pagination | 642-6 | lld:pubmed |
| pubmed-article:10581483 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:10581483 | pubmed:meshHeading | pubmed-meshheading:10581483... | lld:pubmed |
| pubmed-article:10581483 | pubmed:meshHeading | pubmed-meshheading:10581483... | lld:pubmed |
| pubmed-article:10581483 | pubmed:meshHeading | pubmed-meshheading:10581483... | lld:pubmed |
| pubmed-article:10581483 | pubmed:meshHeading | pubmed-meshheading:10581483... | lld:pubmed |
| pubmed-article:10581483 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10581483 | pubmed:articleTitle | Cognitive deficits in normally intelligent patients with tuberous sclerosis. | lld:pubmed |
| pubmed-article:10581483 | pubmed:affiliation | Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom. john.harrison@cenes.co.uk | lld:pubmed |
| pubmed-article:10581483 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10581483 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10581483 | lld:pubmed |
