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pubmed-article:10574779pubmed:abstractTextThe Escherichia coli peptide antibiotic microcin B17 (MccB17) contains thiazole and oxazole heterocycles derived from a distributive yet directional cyclization of cysteines and serines in the McbA precursor catalyzed by MccB17 synthetase. Whether the formation of upstream rings potentiates downstream heterocyclization has not been previously determined.lld:pubmed
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pubmed-article:10574779pubmed:articleTitleExpressed protein ligation to probe regiospecificity of heterocyclization in the peptide antibiotic microcin B17.lld:pubmed
pubmed-article:10574779pubmed:affiliationDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.lld:pubmed
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