pubmed-article:10563060 | pubmed:abstractText | Lithium is a difficult drug to use. Although it is effective in the management of mania, manic-depressive illness and recurrent depression, its unwanted effects are troublesome and the dose needs to be titrated against measurements of blood levels. With care, however, the risks can be minimized. Here we discuss lithium and approaches to optimize its use. | lld:pubmed |