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pubmed-article:10562684pubmed:abstractTextPrognosis of head and neck squamous cell carcinoma (HNSCC) is strongly associated with cervical lymph node metastasis. Cathepsin-D is a lysosomal protease expressed in all cells. Its role in extracellular matrix degradation is postulated to promote tumor invasion and metastasis. Increased cathepsin-D has been demonstrated in cervical lymph node metastasis in HNSCC.lld:pubmed
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pubmed-article:10562684pubmed:copyrightInfoCopyright 1999 John Wiley & Sons, Inc. Head Neck 21: 718-722, 1999.lld:pubmed
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pubmed-article:10562684pubmed:articleTitlePredictive value of cathepsin-D for cervical lymph node metastasis in head and neck squamous cell carcinoma.lld:pubmed
pubmed-article:10562684pubmed:affiliationDepartment of Pathology, University of California Davis, 2315 Stockton Blvd, Sacramento, California, USA.lld:pubmed
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