pubmed-article:10551412 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10551412 | lifeskim:mentions | umls-concept:C0349658 | lld:lifeskim |
pubmed-article:10551412 | lifeskim:mentions | umls-concept:C0681840 | lld:lifeskim |
pubmed-article:10551412 | pubmed:issue | 8 | lld:pubmed |
pubmed-article:10551412 | pubmed:dateCreated | 1999-11-18 | lld:pubmed |
pubmed-article:10551412 | pubmed:abstractText | Accurate histopathologic distinction between trichoepithelioma (TE) and basal cell carcinoma (BCC) may be challenging. From 97 cases diagnosed as TE during the period 1979-1997, 73 available cases were studied with regard to: 1) stroma; 2) retraction effect; 3) papillary-mesenchymal bodies (PMB); 4) amyloid; 5) mitotic figures; 6) apoptotic cells; 7) inflammation; 8) granuloma; and 9) calcification. A judgment was made regarding diagnosis. The patients' medical records were subsequently reviewed for clinical features and possible recurrence. The diagnosis of TE was confirmed histologically in 48 (65%) of 73 cases. Fifteen cases (21%) were reclassified as BCC (RC-BCC), eight other cases (11%) were reclassified as other lesions, and two additional cases (3%) could not be confidently classified as either TE or BCC. The most helpful differentiating features were the presence of retraction effect (in 100% of RC-BCC vs. 37% of TE), myxoid stroma (in 80% of RC-BCC vs. 12% of TE) and PMB (in 20% of RC-BCC vs. 81% of TE). Unexpected findings in TE were detection of amyloid in 33%, apoptotic cells in 100%, and mitotic figures in 46%. Five of the 15 RC-BCC have recurred (33%), whereas there have been no recurrences in the confirmed TE group. A constellation of histopathologic criteria may help to discriminate problematic examples of trichoepithelioma from basal cell carcinoma. | lld:pubmed |
pubmed-article:10551412 | pubmed:language | eng | lld:pubmed |
pubmed-article:10551412 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10551412 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10551412 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10551412 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10551412 | pubmed:month | Sep | lld:pubmed |
pubmed-article:10551412 | pubmed:issn | 0303-6987 | lld:pubmed |
pubmed-article:10551412 | pubmed:author | pubmed-author:SheaC RCR | lld:pubmed |
pubmed-article:10551412 | pubmed:author | pubmed-author:PrietoV GVG | lld:pubmed |
pubmed-article:10551412 | pubmed:author | pubmed-author:BettencourtM... | lld:pubmed |
pubmed-article:10551412 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10551412 | pubmed:volume | 26 | lld:pubmed |
pubmed-article:10551412 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10551412 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10551412 | pubmed:pagination | 398-404 | lld:pubmed |
pubmed-article:10551412 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:10551412 | pubmed:year | 1999 | lld:pubmed |
pubmed-article:10551412 | pubmed:articleTitle | Trichoepithelioma: a 19-year clinicopathologic re-evaluation. | lld:pubmed |
pubmed-article:10551412 | pubmed:affiliation | Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA. | lld:pubmed |
pubmed-article:10551412 | pubmed:publicationType | Journal Article | lld:pubmed |