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pubmed-article:10551381pubmed:abstractTextHepatitis C virus (HCV) infection is often associated with mixed cryoglobulins (MC) and may manifest as small-vessel vasculitis. It has been suggested that antibody (Ab) or sensitized T cells to HCV-containing endothelial cells may initiate the vasculitis process. Anti-endothelial cell antibodies (AECA) have been found in various connective tissue disorders, with a high prevalence in systemic vasculitis. The aim of the study was to determine the prevalence of AECA in HCV patients with or without MC-associated vasculitis, and to identify associations with clinical, immunological, virological and liver characteristics.lld:pubmed
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pubmed-article:10551381pubmed:articleTitleAnti-endothelial cell auto-antibodies in hepatitis C virus mixed cryoglobulinemia.lld:pubmed
pubmed-article:10551381pubmed:affiliationDepartment of Internal Medicine, Hôpital La Pitié-Salpêtrière, Paris, France. patrice.cacoub@psl.ap-hop-paris.frlld:pubmed
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