| pubmed-article:10549292 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C0001527 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C0007589 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C0166417 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C1511938 | lld:lifeskim |
| pubmed-article:10549292 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:10549292 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:10549292 | pubmed:dateCreated | 1999-11-26 | lld:pubmed |
| pubmed-article:10549292 | pubmed:abstractText | The process of adipogenesis is known to involve the interplay of several transcription factors. Activation of one of these factors, the nuclear hormone receptor PPAR gamma, is known to promote fat cell differentiation in vitro. Whether PPAR gamma is required for this process in vivo has remained an open question because a viable loss-of-function model for PPAR gamma has been lacking. We demonstrate here that mice chimeric for wild-type and PPAR gamma null cells show little or no contribution of null cells to adipose tissue, whereas most other organs examined do not require PPAR gamma for proper development. In vitro, the differentiation of ES cells into fat is shown to be dependent on PPAR gamma gene dosage. These data provide direct evidence that PPAR gamma is essential for the formation of fat. | lld:pubmed |
| pubmed-article:10549292 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10549292 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10549292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10549292 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10549292 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:10549292 | pubmed:issn | 1097-2765 | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:MooreKK | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:MortensenR... | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:MilstoneD SDS | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:RosenE DED | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:SpiegelmanB... | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:BradwinGG | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:SarrafPP | lld:pubmed |
| pubmed-article:10549292 | pubmed:author | pubmed-author:TroyA EAE | lld:pubmed |
| pubmed-article:10549292 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10549292 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:10549292 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10549292 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10549292 | pubmed:pagination | 611-7 | lld:pubmed |
| pubmed-article:10549292 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:meshHeading | pubmed-meshheading:10549292... | lld:pubmed |
| pubmed-article:10549292 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10549292 | pubmed:articleTitle | PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. | lld:pubmed |
| pubmed-article:10549292 | pubmed:affiliation | Dana Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA. | lld:pubmed |
| pubmed-article:10549292 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10549292 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10549292 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:19016 | entrezgene:pubmed | pubmed-article:10549292 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10549292 | lld:pubmed |
