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pubmed-article:10543670pubmed:abstractTextPopulation-based epidemiological studies have shown that infection with dengue type 2 (DEN-2) virus in individuals previously infected with a different serotype of the virus is a major risk factor for dengue haemorrhagic fever and dengue shock syndrome. However, the western hemisphere was spared epidemics of these two syndromes, until the introduction of a southeast Asian DEN-2 genotype. Possibly American DEN-2 genotype strains lacked properties necessary to cause severe disease. We report on a major epidemic of DEN-2 in Peru in 1995, about 5 years after an epidemic of DEN-1 in the same population.lld:pubmed
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pubmed-article:10543670pubmed:affiliationNaval Medical Research Center Detachment, AMEMB-NAMRID, Unit 3800, Lima, Peru. Watts@namrid.sld.pelld:pubmed
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