Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase.

Source:http://linkedlifedata.com/resource/pubmed/id/10542297

J. Biol. Chem. 1999 Nov 5 274 45 32507-11

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10542297