pubmed-article:10532233 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0162867 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0002505 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0001128 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0679199 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0007996 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0231448 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
pubmed-article:10532233 | lifeskim:mentions | umls-concept:C0442821 | lld:lifeskim |
pubmed-article:10532233 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:10532233 | pubmed:dateCreated | 1999-11-2 | lld:pubmed |
pubmed-article:10532233 | pubmed:abstractText | The synthesis of hydrazinopeptides using solid-phase N-electrophilic amination was extended to the Fmoc/tert-butyl strategy. Both Boc/benzyl and Fmoc/tert-butyl strategies led to the isolation of by-products arising from the partial instability of the N-N bond during the final cleavage and deprotection step. Two paths of decomposition have been shown: the cleavage of the N-N bond leading to the regeneration of the amine and a Hofmann-type elimination yielding original dianisyl adducts. Our data suggest that the Fmoc/tert-butyl strategy is better suited for the synthesis of hydrazinopeptides. | lld:pubmed |
pubmed-article:10532233 | pubmed:language | eng | lld:pubmed |
pubmed-article:10532233 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10532233 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10532233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10532233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10532233 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10532233 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10532233 | pubmed:month | Oct | lld:pubmed |
pubmed-article:10532233 | pubmed:issn | 1397-002X | lld:pubmed |
pubmed-article:10532233 | pubmed:author | pubmed-author:SamsonFF | lld:pubmed |
pubmed-article:10532233 | pubmed:author | pubmed-author:BonnetDD | lld:pubmed |
pubmed-article:10532233 | pubmed:author | pubmed-author:RommensCC | lld:pubmed |
pubmed-article:10532233 | pubmed:author | pubmed-author:Gras-MasseHH | lld:pubmed |
pubmed-article:10532233 | pubmed:author | pubmed-author:MelnykOO | lld:pubmed |
pubmed-article:10532233 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10532233 | pubmed:volume | 54 | lld:pubmed |
pubmed-article:10532233 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10532233 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10532233 | pubmed:pagination | 270-8 | lld:pubmed |
pubmed-article:10532233 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:meshHeading | pubmed-meshheading:10532233... | lld:pubmed |
pubmed-article:10532233 | pubmed:year | 1999 | lld:pubmed |
pubmed-article:10532233 | pubmed:articleTitle | Synthesis of hydrazinopeptides using solid-phase N-electrophilic amination: extension to the Fmoc/tert-butyl strategy and chemistry of the N-N bond in strong acid media. | lld:pubmed |
pubmed-article:10532233 | pubmed:affiliation | Institut Pasteur de Lille/Institut de Biologie de Lille, France. | lld:pubmed |
pubmed-article:10532233 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:10532233 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |