| pubmed-article:10514008 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C0597722 | lld:lifeskim |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C0680730 | lld:lifeskim |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C1334889 | lld:lifeskim |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C1148554 | lld:lifeskim |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C1881379 | lld:lifeskim |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:10514008 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:10514008 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10514008 | pubmed:dateCreated | 1999-10-26 | lld:pubmed |
| pubmed-article:10514008 | pubmed:abstractText | Notch receptors regulate fate decisions in many cells. One outcome of Notch signaling is differentiation of bipotential precursors into one cell type versus another. To investigate consequences of Notch1 expression in hematolymphoid progenitors, mice were reconstituted with bone marrow (BM) transduced with retroviruses encoding a constitutively active form of Notch1. Although neither granulocyte or monocyte differentiation were appreciably affected, lymphopoiesis was dramatically altered. As early as 3 weeks following transplantation, mice receiving activated Notch1-transduced BM contained immature CD4+ CD8+ T cells in the BM and exhibited a simultaneous block in early B cell lymphopoiesis. These results suggest that Notch1 provides a key regulatory signal in determining T lymphoid versus B lymphoid lineage decisions, possibly by influencing lineage commitment from a common lymphoid progenitor cell. | lld:pubmed |
| pubmed-article:10514008 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10514008 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10514008 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10514008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10514008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10514008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10514008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10514008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10514008 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10514008 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10514008 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:10514008 | pubmed:issn | 1074-7613 | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:LeeJ YJY | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:AsterJ CJC | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:YUMM | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:HardyR RRR | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:DeyN CNC | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:KadeschTT | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:PeayW JWJ | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:AllmanDD | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:DeRoccoSS | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:KarnellF GFG | lld:pubmed |
| pubmed-article:10514008 | pubmed:author | pubmed-author:BakkourSS | lld:pubmed |
| pubmed-article:10514008 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10514008 | pubmed:volume | 11 | lld:pubmed |
| pubmed-article:10514008 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10514008 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10514008 | pubmed:pagination | 299-308 | lld:pubmed |
| pubmed-article:10514008 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:meshHeading | pubmed-meshheading:10514008... | lld:pubmed |
| pubmed-article:10514008 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10514008 | pubmed:articleTitle | Notch1 expression in early lymphopoiesis influences B versus T lineage determination. | lld:pubmed |
| pubmed-article:10514008 | pubmed:affiliation | Department of Pathology and Laboratory Medicine and Institute of Medicine and Engineering, University of Pennsylvania Medical Center, Philadelphia 19104, USA. | lld:pubmed |
| pubmed-article:10514008 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10514008 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10514008 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:18128 | entrezgene:pubmed | pubmed-article:10514008 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10514008 | lld:pubmed |
