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pubmed-article:10498203pubmed:abstractTextSynthetic dysidiolide, as well as several related compounds containing a gamma-hydroxybutenolide moiety, were tested in in vitro Cdc25 assays against both synthetic and natural substrates. Contrary to literature values which are in the low micromolar range, we observe only millimolar inhibitory activity for these compounds versus Cdc25 phosphatase.lld:pubmed
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pubmed-article:10498203pubmed:articleTitleDysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25.lld:pubmed
pubmed-article:10498203pubmed:affiliationDepartment of Biochemistry, Mitotix, Inc., Cambridge MA 02139, USA.lld:pubmed
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