| pubmed-article:10485890 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C0027754 | lld:lifeskim |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C0080347 | lld:lifeskim |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C0027752 | lld:lifeskim |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C1704711 | lld:lifeskim |
| pubmed-article:10485890 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:10485890 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:10485890 | pubmed:dateCreated | 1999-10-14 | lld:pubmed |
| pubmed-article:10485890 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:abstractText | A subclass of zinc finger proteins containing a unique protein motif called the positive regulatory (PR) domain has been described. The members include the PRDI-BF1/Blimp-1 protein, the Caenorhabditis elegans egl-43 and EVI1 gene products, and the retinoblastoma interacting protein RIZ. Here we describe a member of this family, SC-1, that exhibits several distinctive features. First, SC-1 interacts with the p75 neurotrophin receptor and is redistributed from the cytoplasm to the nucleus after nerve growth factor (NGF) treatment of transfected COS cells. The translocation of SC-1 to the nucleus was specific for p75, as NGF binding to the TrkA receptor did not lead to nuclear localization of SC-1. Thus, SC-1 provides a downstream transducer for the effects of NGF through the p75 neurotrophin receptor. Under normal growth conditions, SC-1 was found predominantly in the cytoplasm. On serum-starvation, SC-1 also translocated into the nucleus. A direct correlation between nuclear expression of SC-1 with the loss of BrdUrd incorporation was observed. These results imply that SC-1 may be involved in events associated with growth arrest. | lld:pubmed |
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| pubmed-article:10485890 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10485890 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10485890 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10485890 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:10485890 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:10485890 | pubmed:author | pubmed-author:ChaoM VMV | lld:pubmed |
| pubmed-article:10485890 | pubmed:author | pubmed-author:ChittkaAA | lld:pubmed |
| pubmed-article:10485890 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10485890 | pubmed:day | 14 | lld:pubmed |
| pubmed-article:10485890 | pubmed:volume | 96 | lld:pubmed |
| pubmed-article:10485890 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10485890 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10485890 | pubmed:pagination | 10705-10 | lld:pubmed |
| pubmed-article:10485890 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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