| pubmed-article:10479128 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10479128 | lifeskim:mentions | umls-concept:C0019682 | lld:lifeskim |
| pubmed-article:10479128 | lifeskim:mentions | umls-concept:C0521026 | lld:lifeskim |
| pubmed-article:10479128 | lifeskim:mentions | umls-concept:C0027361 | lld:lifeskim |
| pubmed-article:10479128 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
| pubmed-article:10479128 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:10479128 | lifeskim:mentions | umls-concept:C0205470 | lld:lifeskim |
| pubmed-article:10479128 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:10479128 | pubmed:dateCreated | 1999-11-8 | lld:pubmed |
| pubmed-article:10479128 | pubmed:abstractText | Persons who were human immunodeficiency virus type 1 (HIV-1)-infected but who remained persistently seronegative (HIPS) on HIV-1 antibody tests were examined through AIDS case surveillance. Six such individuals (HIPS-1 to -4, -7, and -9) were examined to determine whether their persistent seronegativity was attributable to immune dysfunction or infection with atypical HIV. Of the 6, 4 had antibody titers to at least 1 other common pathogen. In vitro stimulation of peripheral blood mononuclear cells from HIPS-4 and HIPS-7 with pokeweed mitogen or phosphorothioate oligodeoxynucleotide (direct B cell mitogen) did not produce HIV-1-specific antibody. Reconstitution experiments with recombinant interleukin (rIL)-4 and rIL-12 also had no impact on antibody production. Virus isolates from HIPS-4 and -9 were R5X4-tropic, whereas HIPS-7 was CCR5-tropic only. Sequence analysis of long terminal repeat, p24, and env gp41 did not reveal any specific mutation, and phylogenetic analysis confirmed that all 6 virus specimens were HIV-1 subtype B. These data suggest that the lack of a detectable antibody response in these patients may be the result of immune dysfunction. | lld:pubmed |
| pubmed-article:10479128 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10479128 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10479128 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10479128 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:10479128 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:10479128 | pubmed:author | pubmed-author:SullivanP SPS | lld:pubmed |
| pubmed-article:10479128 | pubmed:author | pubmed-author:SpiraT JTJ | lld:pubmed |
| pubmed-article:10479128 | pubmed:author | pubmed-author:FolksT MTM | lld:pubmed |
| pubmed-article:10479128 | pubmed:author | pubmed-author:DornJJ | lld:pubmed |
| pubmed-article:10479128 | pubmed:author | pubmed-author:LalR BRB | lld:pubmed |
| pubmed-article:10479128 | pubmed:author | pubmed-author:EllenbergerD... | lld:pubmed |
| pubmed-article:10479128 | pubmed:author | pubmed-author:SchableCC | lld:pubmed |
| pubmed-article:10479128 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10479128 | pubmed:volume | 180 | lld:pubmed |
| pubmed-article:10479128 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10479128 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10479128 | pubmed:pagination | 1033-42 | lld:pubmed |
| pubmed-article:10479128 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:meshHeading | pubmed-meshheading:10479128... | lld:pubmed |
| pubmed-article:10479128 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10479128 | pubmed:articleTitle | Viral and immunologic examination of human immunodeficiency virus type 1-infected, persistently seronegative persons. | lld:pubmed |
| pubmed-article:10479128 | pubmed:affiliation | HIV/AIDS Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. dxe1@cdc.gov | lld:pubmed |
| pubmed-article:10479128 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10479128 | lld:pubmed |
