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pubmed-article:10475637pubmed:abstractText1. Three experiments were conducted with broiler chickens using hypobaric chambers and control pens, feeding diets containing 25 or 50 g flax oil/kg food or control diets with equivalent amounts of animal/vegetable (A/V) blend oil for 4 weeks. The effect of these diets on haematological variables and the extent of right ventricular hypertrophy (RVH) leading to ascites was determined. 2. Overall growth rate was not consistently affected by dietary treatment, although feeding the 25 g flax oil/kg diet reduced weight gain in week 4 of one experiment. Feeding the 50 g flax oil/kg diet but not the 25 g flax oil/kg diet reduced RVH in birds exposed to hypobaric conditions compared to feeding control diets. 3. Feeding the 50 g flax oil/kg diet under hypobaric conditions reduced the haematocrit and haemoglobin content, increased the erythrocyte deformability and the proportion of unsaturated fatty acids in the erythrocyte membranes, and reduced the whole blood viscosity compared to feeding control diets. These effects were not seen when the 25 g flax oil/kg diet was fed. The ratio of n-3 to n-6 fatty acids in erythrocyte membranes was increased in the 50 g flax oil/kg treatment group compared to controls. 4. Including 50 g flax oil/kg broiler diet reduces RVH in broiler chickens. This may be attributable in part to an increase in erythrocyte deformability from an increased proportion of unsaturated fatty acids in the erythrocyte membranes.lld:pubmed
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pubmed-article:10475637pubmed:authorpubmed-author:SquiresE JEJlld:pubmed
pubmed-article:10475637pubmed:authorpubmed-author:JulianR JRJlld:pubmed
pubmed-article:10475637pubmed:authorpubmed-author:BondJ MJMlld:pubmed
pubmed-article:10475637pubmed:authorpubmed-author:WaltonJ PJPlld:pubmed
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pubmed-article:10475637pubmed:pagination385-91lld:pubmed
pubmed-article:10475637pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:10475637pubmed:articleTitleEffect of dietary flax oil and hypobaric hypoxia on pulmonary hypertension and haematological variables in broiler chickens.lld:pubmed
pubmed-article:10475637pubmed:affiliationDepartment of Animal and Poultry Science, University of Guelph, Ontario, Canada.lld:pubmed
pubmed-article:10475637pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10475637pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed