| pubmed-article:10471395 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C0596995 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C0262950 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C0029418 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C0007589 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C1511938 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C1881379 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C1510800 | lld:lifeskim |
| pubmed-article:10471395 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:10471395 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10471395 | pubmed:dateCreated | 1999-10-7 | lld:pubmed |
| pubmed-article:10471395 | pubmed:abstractText | To examine the effectiveness of a gene transfer of bone morphogenetic protein (BMP)-2 into C2C12 myoblasts, we constructed a human BMP-2-expressing replication-deficient adenoviral vector, AxCAOBMP-2. C2C12 cells were infected in vitro with either this viral vector or an Escherichia coli LacZ gene-expressing control adenovirus vector. An efficient gene transfer to the C2C12 cells was confirmed with the LacZ gene-expressing vector by X-gal staining. Abundant BMP-2 expression in C2C12 cells infected with this viral vector was confirmed by immunofluorescence and Western blot analysis. C2C12 cells transferred with the BMP-2 gene by this vector produced alkaline phosphatase in the cells and also produced and secreted osteocalcin in the culture medium, demonstrating that a gene transfer of BMP-2 into C2C12 cells in vitro could convert these cells from myoblast to osteoblast lineage. | lld:pubmed |
| pubmed-article:10471395 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10471395 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10471395 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10471395 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:10471395 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:10471395 | pubmed:author | pubmed-author:IizukaTT | lld:pubmed |
| pubmed-article:10471395 | pubmed:author | pubmed-author:OkuboYY | lld:pubmed |
| pubmed-article:10471395 | pubmed:author | pubmed-author:FujimuraKK | lld:pubmed |
| pubmed-article:10471395 | pubmed:author | pubmed-author:MiyatakeSS | lld:pubmed |
| pubmed-article:10471395 | pubmed:author | pubmed-author:BesshoKK | lld:pubmed |
| pubmed-article:10471395 | pubmed:copyrightInfo | Copyright 1999 Academic Press. | lld:pubmed |
| pubmed-article:10471395 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10471395 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:10471395 | pubmed:volume | 262 | lld:pubmed |
| pubmed-article:10471395 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10471395 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10471395 | pubmed:pagination | 739-43 | lld:pubmed |
| pubmed-article:10471395 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:10471395 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10471395 | pubmed:articleTitle | Expression of bone morphogenetic protein-2 via adenoviral vector in C2C12 myoblasts induces differentiation into the osteoblast lineage. | lld:pubmed |
| pubmed-article:10471395 | pubmed:affiliation | Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. | lld:pubmed |
| pubmed-article:10471395 | pubmed:publicationType | Journal Article | lld:pubmed |
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