| pubmed-article:10464876 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10464876 | lifeskim:mentions | umls-concept:C0004096 | lld:lifeskim |
| pubmed-article:10464876 | lifeskim:mentions | umls-concept:C0021368 | lld:lifeskim |
| pubmed-article:10464876 | lifeskim:mentions | umls-concept:C0038056 | lld:lifeskim |
| pubmed-article:10464876 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:10464876 | lifeskim:mentions | umls-concept:C1516048 | lld:lifeskim |
| pubmed-article:10464876 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:10464876 | pubmed:dateCreated | 1999-9-28 | lld:pubmed |
| pubmed-article:10464876 | pubmed:abstractText | Sputum induction can be used to study airway inflammation in asthmatics. However, it has not been used in patients with corticosteroid-dependent asthma requiring long-term oral corticosteroids. The aim of the study was to assess the number of eosinophils and the levels of eosinophil cationic protein (ECP) in sputum of 17 corticosteroid-dependent asthmatics by comparison with nine mild untreated asthmatics, 10 moderate asthmatics receiving inhaled steroids (ICS) and 11 healthy subjects. In the 17 corticosteroid-dependent asthmatics, we examined sputum eosinophil markers on two occasions and correlated with the control of asthma. Eosinophils were undetectable in controls and were detected in 63.8% of asthmatics. There were no significant differences between the three groups of asthmatics. ECP levels were significantly increased in ICS or corticosteroid-dependent asthmatics by comparison to controls and mild asthmatics. There was no significant difference between ICS and corticosteroid-dependent asthmatics. During follow-up, corticosteroid-dependent asthmatics with a controlled disease had no significant change in eosinophil numbers or ECP levels. On the other hand, corticosteroid-dependent asthmatics with recent exacerbations had a non-significant increase in eosinophil numbers and a significant increase in ECP levels. This study shows that ECP levels may be more accurate than eosinophil numbers in assessing exacerbations in corticosteroid-dependent asthmatics. | lld:pubmed |
| pubmed-article:10464876 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10464876 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10464876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10464876 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10464876 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:10464876 | pubmed:issn | 0954-6111 | lld:pubmed |
| pubmed-article:10464876 | pubmed:author | pubmed-author:BousquetJJ | lld:pubmed |
| pubmed-article:10464876 | pubmed:author | pubmed-author:CarlssonLL | lld:pubmed |
| pubmed-article:10464876 | pubmed:author | pubmed-author:GodardPP | lld:pubmed |
| pubmed-article:10464876 | pubmed:author | pubmed-author:ChanezPP | lld:pubmed |
| pubmed-article:10464876 | pubmed:author | pubmed-author:RomagnoliMM | lld:pubmed |
| pubmed-article:10464876 | pubmed:author | pubmed-author:Tarodo de... | lld:pubmed |
| pubmed-article:10464876 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10464876 | pubmed:volume | 93 | lld:pubmed |
| pubmed-article:10464876 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10464876 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10464876 | pubmed:pagination | 183-9 | lld:pubmed |
| pubmed-article:10464876 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
| pubmed-article:10464876 | pubmed:meshHeading | pubmed-meshheading:10464876... | lld:pubmed |
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| pubmed-article:10464876 | pubmed:meshHeading | pubmed-meshheading:10464876... | lld:pubmed |
| pubmed-article:10464876 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10464876 | pubmed:articleTitle | Eosinophilic inflammation assessed by induced sputum in corticosteroid-dependent asthma. | lld:pubmed |
| pubmed-article:10464876 | pubmed:affiliation | Service des Maladies Respiratoires, INSERM U454, Hôpital Arnaud de Villeneuve, Montpellier, France. | lld:pubmed |
| pubmed-article:10464876 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10464876 | lld:pubmed |
