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| pubmed-article:10417205 | lifeskim:mentions | umls-concept:C0020964 | lld:lifeskim |
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| pubmed-article:10417205 | lifeskim:mentions | umls-concept:C0442117 | lld:lifeskim |
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| pubmed-article:10417205 | lifeskim:mentions | umls-concept:C0443324 | lld:lifeskim |
| pubmed-article:10417205 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:10417205 | pubmed:dateCreated | 1999-8-12 | lld:pubmed |
| pubmed-article:10417205 | pubmed:abstractText | Immunization of mice by the intranasal route with influenza virus hemagglutinin in combination with the mutant Escherichia coli heat-labile enterotoxin R72 (LT-R72) induced significantly enhanced serum and mucosal antibodies, surpassing, in most cases, responses achieved by traditional intramuscular immunization using inactivated split influenza vaccine. Furthermore, intranasal immunization with LT-R72 induced a potent serum immunoglobulin G2a response, indicating that this adjuvant has Th1 character. | lld:pubmed |
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| pubmed-article:10417205 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:10417205 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:10417205 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10417205 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:10417205 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:10417205 | pubmed:author | pubmed-author:OttGG | lld:pubmed |
| pubmed-article:10417205 | pubmed:author | pubmed-author:O'HaganD TDT | lld:pubmed |
| pubmed-article:10417205 | pubmed:author | pubmed-author:BarackmanJ... | lld:pubmed |
| pubmed-article:10417205 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10417205 | pubmed:volume | 67 | lld:pubmed |
| pubmed-article:10417205 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10417205 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10417205 | pubmed:pagination | 4276-9 | lld:pubmed |
| pubmed-article:10417205 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:10417205 | pubmed:meshHeading | pubmed-meshheading:10417205... | lld:pubmed |
| pubmed-article:10417205 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10417205 | pubmed:articleTitle | Intranasal immunization of mice with influenza vaccine in combination with the adjuvant LT-R72 induces potent mucosal and serum immunity which is stronger than that with traditional intramuscular immunization. | lld:pubmed |
| pubmed-article:10417205 | pubmed:affiliation | Chiron Corporation, Emeryville, California, USA. john.barackman@cc.chiron.com | lld:pubmed |
| pubmed-article:10417205 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10417205 | pubmed:publicationType | Comparative Study | lld:pubmed |
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