| pubmed-article:10415725 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C0679215 | lld:lifeskim |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C0150369 | lld:lifeskim |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C0172956 | lld:lifeskim |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C0039593 | lld:lifeskim |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C0205369 | lld:lifeskim |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C0036397 | lld:lifeskim |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C1518987 | lld:lifeskim |
| pubmed-article:10415725 | lifeskim:mentions | umls-concept:C1527178 | lld:lifeskim |
| pubmed-article:10415725 | pubmed:dateCreated | 1999-8-11 | lld:pubmed |
| pubmed-article:10415725 | pubmed:abstractText | Matrix metalloproteinases (MMPs), especially collagenase-2 (MMP-8), are key mediators of irreversible tissue destruction associated with periodontitis and peri-implantitis. MMP-8 is known to exist in elevated amounts and in active form in the gingival crevicular fluid (GCF) and peri-implant sulcular fluid (PISF) from progressing periodontitis and peri-implantitis lesions and sites, respectively. (Sorsa et al. Ann. N.Y. Acad. Sci. 737: 112-131 [1994]; Teronen et al. J. Dent. Res. 76: 1529-1537 [1997]). We have developed monoclonal antibodies to MMP-8 (Hanemaaijer et al. J. Biol. Chem. 272: 31504-31509 [1997]) that can be used in a chair-side dipstick test to monitor the course and treatment of periodontitis and peri-implantitis. Monoclonal and polyclonal antibody tests for MMP-8 coincided with the classical functional collagenase activity test from GCF and PISF (Sorsa et al. J. Periodont. Res. 22: 386-393 [1988]) in periodontal and peri-implant health and disease. In future a chair-side functional and/or immunological MMP-test can be useful to diagnose and monitor periodontal and peri-implant disease and health. | lld:pubmed |
| pubmed-article:10415725 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10415725 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10415725 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10415725 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10415725 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10415725 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10415725 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10415725 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10415725 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:10415725 | pubmed:issn | 0077-8923 | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:GolubL MLM | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:LundqvistCC | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:SorsaTT | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:SalaFF | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:KallioPP | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:KinaneD FDF | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:TikanojaSS | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:MäntyläPP | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:KallisG BGB | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:TeronenOO | lld:pubmed |
| pubmed-article:10415725 | pubmed:author | pubmed-author:RönkäHH | lld:pubmed |
| pubmed-article:10415725 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10415725 | pubmed:day | 30 | lld:pubmed |
| pubmed-article:10415725 | pubmed:volume | 878 | lld:pubmed |
| pubmed-article:10415725 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10415725 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10415725 | pubmed:pagination | 130-40 | lld:pubmed |
| pubmed-article:10415725 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10415725 | pubmed:meshHeading | pubmed-meshheading:10415725... | lld:pubmed |
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| pubmed-article:10415725 | pubmed:meshHeading | pubmed-meshheading:10415725... | lld:pubmed |
| pubmed-article:10415725 | pubmed:meshHeading | pubmed-meshheading:10415725... | lld:pubmed |
| pubmed-article:10415725 | pubmed:meshHeading | pubmed-meshheading:10415725... | lld:pubmed |
| pubmed-article:10415725 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10415725 | pubmed:articleTitle | Scientific basis of a matrix metalloproteinase-8 specific chair-side test for monitoring periodontal and peri-implant health and disease. | lld:pubmed |
| pubmed-article:10415725 | pubmed:affiliation | Department of Periodontology, University of Helsinki, Finland. tsorsa@hammas.helsinki.fi | lld:pubmed |
| pubmed-article:10415725 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10415725 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:10415725 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10415725 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10415725 | lld:pubmed |
