| pubmed-article:10400619 | rdf:type | pubmed:Citation | lld:pubmed |
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| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C0009015 | lld:lifeskim |
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| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C0597874 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C1515670 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C1136254 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C0086022 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C2827424 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C1705099 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C0442335 | lld:lifeskim |
| pubmed-article:10400619 | lifeskim:mentions | umls-concept:C0322859 | lld:lifeskim |
| pubmed-article:10400619 | pubmed:issue | 29 | lld:pubmed |
| pubmed-article:10400619 | pubmed:dateCreated | 1999-8-19 | lld:pubmed |
| pubmed-article:10400619 | pubmed:abstractText | An antimicrobial peptide belonging to the cecropin family was isolated from the hemolymph of bacteria-challenged adult Aedes aegypti. This new peptide, named cecropin A, was purified to homogeneity and fully characterized after cDNA cloning. The 34-residue A. aegypti cecropin A is different from the majority of reported insect cecropins in that it is devoid of a tryptophan residue and C-terminal amidation. The importance of these two structural features on the activity spectrum was investigated using a chemically synthesized peptide. A comparison of the antimicrobial activity spectrum of A. aegypti and Drosophila cecropin A showed a lower activity for the mosquito molecule. A. aegypti cecropin mRNA expression was not detected by Northern blot or reverse transcription-polymerase chain reaction analysis in any immature stage of the mosquito, nor in naïve adults, but it was observed in challenged adults 6 h after bacteria inoculation, and it continued over 7-10 days. | lld:pubmed |
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| pubmed-article:10400619 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10400619 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10400619 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:10400619 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10400619 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:10400619 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:10400619 | pubmed:author | pubmed-author:RichmanAA | lld:pubmed |
| pubmed-article:10400619 | pubmed:author | pubmed-author:KambeKK | lld:pubmed |
| pubmed-article:10400619 | pubmed:author | pubmed-author:CharletMM | lld:pubmed |
| pubmed-article:10400619 | pubmed:author | pubmed-author:ChristensenB... | lld:pubmed |
| pubmed-article:10400619 | pubmed:author | pubmed-author:BuletPP | lld:pubmed |
| pubmed-article:10400619 | pubmed:author | pubmed-author:VizioliJJ | lld:pubmed |
| pubmed-article:10400619 | pubmed:author | pubmed-author:LowenbergerCC | lld:pubmed |
| pubmed-article:10400619 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10400619 | pubmed:day | 16 | lld:pubmed |
| pubmed-article:10400619 | pubmed:volume | 274 | lld:pubmed |
| pubmed-article:10400619 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10400619 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10400619 | pubmed:pagination | 20092-7 | lld:pubmed |
| pubmed-article:10400619 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:10400619 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10400619 | pubmed:articleTitle | Antimicrobial activity spectrum, cDNA cloning, and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti. | lld:pubmed |
| pubmed-article:10400619 | pubmed:affiliation | Animal Health and Biomedical Sciences, University of Wisconsin, Madison, Wisconsin 53706, USA. | lld:pubmed |
| pubmed-article:10400619 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10400619 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10400619 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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