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pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0206131 | lld:lifeskim |
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pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0040715 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0288881 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C1522702 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C1420175 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0599718 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0599813 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0599893 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0086597 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:10394363 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:10394363 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:10394363 | pubmed:dateCreated | 1999-7-16 | lld:pubmed |
pubmed-article:10394363 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10394363 | pubmed:abstractText | Insulin-stimulated glucose transport and GLUT4 translocation require regulated interactions between the v-SNARE, VAMP2, and the t-SNARE, syntaxin 4. We have isolated a novel syntaxin 4-binding protein, Synip, which specifically interacts with syntaxin 4. Insulin induces a dissociation of the Synip:syntaxin 4 complex due to an apparent decrease in the binding affinity of Synip for syntaxin 4. In contrast, the carboxyterminal domain of Synip does not dissociate from syntaxin 4 in response to insulin stimulation but inhibits glucose transport and GLUT4 translocation. These data implicate Synip as an insulin-regulated syntaxin 4-binding protein directly involved in the control of glucose transport and GLUT4 vesicle translocation. | lld:pubmed |
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pubmed-article:10394363 | pubmed:language | eng | lld:pubmed |
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pubmed-article:10394363 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:10394363 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10394363 | pubmed:month | Jun | lld:pubmed |
pubmed-article:10394363 | pubmed:issn | 1097-2765 | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:NodaYY | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:OkadaSS | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:YuM WMW | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:KanzakiMM | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:PessinJ EJE | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:ColesJ MJM | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:SaltielA RAR | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:SyuL JLJ | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:ElmendorfJ... | lld:pubmed |
pubmed-article:10394363 | pubmed:author | pubmed-author:CeresaB PBP | lld:pubmed |
pubmed-article:10394363 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10394363 | pubmed:volume | 3 | lld:pubmed |
pubmed-article:10394363 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10394363 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10394363 | pubmed:pagination | 751-60 | lld:pubmed |
pubmed-article:10394363 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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pubmed-article:10394363 | pubmed:year | 1999 | lld:pubmed |
pubmed-article:10394363 | pubmed:articleTitle | Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes. | lld:pubmed |
pubmed-article:10394363 | pubmed:affiliation | Department of Cell Biology, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, Michigan 48105, USA. | lld:pubmed |
pubmed-article:10394363 | pubmed:publicationType | Journal Article | lld:pubmed |
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