| pubmed-article:10360784 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10360784 | lifeskim:mentions | umls-concept:C0018555 | lld:lifeskim |
| pubmed-article:10360784 | lifeskim:mentions | umls-concept:C0007610 | lld:lifeskim |
| pubmed-article:10360784 | lifeskim:mentions | umls-concept:C0007009 | lld:lifeskim |
| pubmed-article:10360784 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:10360784 | lifeskim:mentions | umls-concept:C0871738 | lld:lifeskim |
| pubmed-article:10360784 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:10360784 | lifeskim:mentions | umls-concept:C0871935 | lld:lifeskim |
| pubmed-article:10360784 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:10360784 | pubmed:dateCreated | 1999-6-17 | lld:pubmed |
| pubmed-article:10360784 | pubmed:abstractText | To test a possible specific effect of carbon K-shell ionizations in DNA, survival curves for Chinese hamster V79 cells were measured for X irradiations at energies below and above the carbon K-shell ionization threshold. Specific values of the X-ray energies (250 and 340 eV) were chosen to ensure isoattenuation of the two kinds of radiation within the cell. An enhancement of lethality by a factor of about 2 was found for X rays at 340 eV compared to below the threshold at 250 eV. This may be attributed to the production of highly efficient carbon K-shell ionizations located on DNA. A model of X-ray lethality (Goodhead et al., Radiat. Prot. Dosim. 52, 217-223, 1994) was extended to allow for a possible lethal effect from clusters of reactive species induced by K-shell photoionizations (K-shell clusters). Within this model, the increase in lethality above the carbon K-shell threshold may be explained by a value of 2% for the lethal efficiency of K-shell clusters overlapping the DNA. An extrapolation to the lethal effect of more complex ion-induced K-shell ionizations indicates that K-shell ionization may be a major process in the biological effectiveness of heavy ions. | lld:pubmed |
| pubmed-article:10360784 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10360784 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10360784 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10360784 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10360784 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10360784 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10360784 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:10360784 | pubmed:issn | 0033-7587 | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:StevensD LDL | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:GoodheadD TDT | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:HillM AMA | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:AbelFF | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:SabatierLL | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:RicoulMM | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:TouatiAA | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:FayardBB | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:GobertFF | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:ChetiouiAA | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:Herve du... | lld:pubmed |
| pubmed-article:10360784 | pubmed:author | pubmed-author:Despiney-Bail... | lld:pubmed |
| pubmed-article:10360784 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10360784 | pubmed:volume | 151 | lld:pubmed |
| pubmed-article:10360784 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10360784 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10360784 | pubmed:pagination | 649-58 | lld:pubmed |
| pubmed-article:10360784 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:meshHeading | pubmed-meshheading:10360784... | lld:pubmed |
| pubmed-article:10360784 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10360784 | pubmed:articleTitle | Lethal effect of carbon K-shell photoionizations in Chinese hamster V79 cell nuclei: experimental method and theoretical analysis. | lld:pubmed |
| pubmed-article:10360784 | pubmed:affiliation | Groupe de Physique des Solides, Universités Paris 7 et Paris 6 (CNRS UMR 75-88, CEA LRC No.6), France. | lld:pubmed |
| pubmed-article:10360784 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10360784 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
