Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations.

Source:http://linkedlifedata.com/resource/pubmed/id/10359821

Proc. Natl. Acad. Sci. U.S.A. 1999 Jun 8 96 12 6959-63

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10359821