| pubmed-article:10351921 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10351921 | lifeskim:mentions | umls-concept:C0020846 | lld:lifeskim |
| pubmed-article:10351921 | lifeskim:mentions | umls-concept:C1327813 | lld:lifeskim |
| pubmed-article:10351921 | lifeskim:mentions | umls-concept:C0023745 | lld:lifeskim |
| pubmed-article:10351921 | lifeskim:mentions | umls-concept:C0031437 | lld:lifeskim |
| pubmed-article:10351921 | lifeskim:mentions | umls-concept:C2745888 | lld:lifeskim |
| pubmed-article:10351921 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:10351921 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:10351921 | pubmed:dateCreated | 1999-6-29 | lld:pubmed |
| pubmed-article:10351921 | pubmed:abstractText | Chromosome 14q was screened for loci modulating immunoglobulin E (IgE) phenotypes in 15 extended and 45 nuclear asthmatic families using a panel of 14 microsatellite markers. We examined the reported linkage between the TCR A/D locus on 14q11.2 and specific (cognate) allergic responses and observed supportive evidence for linkage between a general skin prick test reactivity trait (but not with total serum IgE) and TCRA microsatellite (in the total sample of informative sib-pairs p = 0.039, in selected sample of one or zero affected parent p = 0.017). We also show suggestive evidence for a novel linkage between markers D14S75 and D14S63 on 14q13-23 and log total serum IgE (p = 0.034 and p = 0.0029). The evidence for linkage with marker D14S63 on 14q23 is strengthened by the finding of association of allele 165 to log IgE (p = 0.0029). We conclude that chromosome 14q may contain a locus close to TCR A/D at 14q11.2 linked to skin prick reactivity and a locus at 14q13- 23 linked to total serum IgE. | lld:pubmed |
| pubmed-article:10351921 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10351921 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10351921 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10351921 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:10351921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10351921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10351921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10351921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10351921 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10351921 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10351921 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:10351921 | pubmed:issn | 1073-449X | lld:pubmed |
| pubmed-article:10351921 | pubmed:author | pubmed-author:MorrisonJ FJF | lld:pubmed |
| pubmed-article:10351921 | pubmed:author | pubmed-author:HolgateS TST | lld:pubmed |
| pubmed-article:10351921 | pubmed:author | pubmed-author:MortonN ENE | lld:pubmed |
| pubmed-article:10351921 | pubmed:author | pubmed-author:MarkhamA FAF | lld:pubmed |
| pubmed-article:10351921 | pubmed:author | pubmed-author:BishopD TDT | lld:pubmed |
| pubmed-article:10351921 | pubmed:author | pubmed-author:MansurA HAH | lld:pubmed |
| pubmed-article:10351921 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10351921 | pubmed:volume | 159 | lld:pubmed |
| pubmed-article:10351921 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10351921 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10351921 | pubmed:pagination | 1796-802 | lld:pubmed |
| pubmed-article:10351921 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:10351921 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10351921 | pubmed:articleTitle | Suggestive evidence for genetic linkage between IgE phenotypes and chromosome 14q markers. | lld:pubmed |
| pubmed-article:10351921 | pubmed:affiliation | Molecular Medicine Unit and ICRF, Ashley Wing, St. James's University Hospital, Leeds, UK. | lld:pubmed |
| pubmed-article:10351921 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10351921 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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