| pubmed-article:10340605 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10340605 | lifeskim:mentions | umls-concept:C0020205 | lld:lifeskim |
| pubmed-article:10340605 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:10340605 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:10340605 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:10340605 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:10340605 | pubmed:dateCreated | 1999-8-19 | lld:pubmed |
| pubmed-article:10340605 | pubmed:abstractText | Geldanamycin (GDM) binds to the Hsp90 chaperone protein and causes the degradation of several important signalling proteins. A series of novel estradiol-geldanamycin hybrids has been synthesized and evaluated for their ability to induce the selective degradation of the estrogen receptor (ER). The hybrid compounds are active and more selective than the parent causing degradation of ER and HER2, but not other GDM targets. | lld:pubmed |
| pubmed-article:10340605 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10340605 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10340605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10340605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10340605 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10340605 | pubmed:month | May | lld:pubmed |
| pubmed-article:10340605 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:10340605 | pubmed:author | pubmed-author:RosenNN | lld:pubmed |
| pubmed-article:10340605 | pubmed:author | pubmed-author:Sepp-Lorenzin... | lld:pubmed |
| pubmed-article:10340605 | pubmed:author | pubmed-author:DanishefskyS... | lld:pubmed |
| pubmed-article:10340605 | pubmed:author | pubmed-author:KudukS DSD | lld:pubmed |
| pubmed-article:10340605 | pubmed:author | pubmed-author:ZhengF FFF | lld:pubmed |
| pubmed-article:10340605 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10340605 | pubmed:day | 3 | lld:pubmed |
| pubmed-article:10340605 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:10340605 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10340605 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10340605 | pubmed:pagination | 1233-8 | lld:pubmed |
| pubmed-article:10340605 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:meshHeading | pubmed-meshheading:10340605... | lld:pubmed |
| pubmed-article:10340605 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10340605 | pubmed:articleTitle | Synthesis and evaluation of geldanamycin-estradiol hybrids. | lld:pubmed |
| pubmed-article:10340605 | pubmed:affiliation | Department of Medicine, Sloan-Kettering Institute for Cancer Research, New York, NY 10021, USA. | lld:pubmed |
| pubmed-article:10340605 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10340605 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10340605 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:10340605 | lld:chembl |
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