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pubmed-article:10335006pubmed:abstractTextPatients with cystic fibrosis experience chronic systemic oxidative stress. This is coupled with chronic inflammation of the lung involving bronchial polymorphonuclear neutrophil accumulation and activation. We hypothesised that, during periods of acute respiratory exacerbation, free radical activity and consequent damage would be most marked and that intensive treatment of the infection would result in improvement towards values found during stable periods.lld:pubmed
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pubmed-article:10335006pubmed:articleTitleOxidative stress during acute respiratory exacerbations in cystic fibrosis.lld:pubmed
pubmed-article:10335006pubmed:affiliationDepartment of Therapeutics and Pharmacology, The Queen's University of Belfast, Belfast BT9 7BL, UK.lld:pubmed
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