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pubmed-article:10334521pubmed:abstractTextp53 gene and K-ras mutations are among the most common genetic alterations present in colorectal cancer. The prognostic utility of such mutations remains controversial. The purpose of this study was to prospectively evaluate the prognostic significance of p53 and K-ras gene mutations in colorectal cancer.lld:pubmed
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pubmed-article:10334521pubmed:articleTitlep53 and K-ras gene mutations correlate with tumor aggressiveness but are not of routine prognostic value in colorectal cancer.lld:pubmed
pubmed-article:10334521pubmed:affiliationDepartment of Cancer and Metastasis, Institut de Recerca Oncològica, Hospital Duran i Reynals, Barcelona, Spain.lld:pubmed
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