pubmed-article:10328182 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0001554 | lld:lifeskim |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0042514 | lld:lifeskim |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0014563 | lld:lifeskim |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0024473 | lld:lifeskim |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0033414 | lld:lifeskim |
pubmed-article:10328182 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:10328182 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:10328182 | pubmed:dateCreated | 1999-7-12 | lld:pubmed |
pubmed-article:10328182 | pubmed:abstractText | The effects of magnesium deficiency on epinephrine-induced ventricular tachyarrhythmia were investigated in adult rats. Forty-two adult Wistar rats were fed a magnesium-deficient diet while 30 rats were fed a standard diet for 20 days. The plasma magnesium concentration was lower in the magnesium-deficient rats (0.22+/-0.01 mmol/l) than in the control rats (0.76+/-0.03 mmol/l, P < 0.001). Using a telemetry system, electrocardiograms and arterial blood pressure were recorded on a polygraph in an unrestrained condition. Epinephrine was infused intravenously starting at 5 microg/kg per minute. The QT interval was prolonged to 50+/-1 ms in the magnesium-deficient rats compared with 44+/-1 ms in the control rats (P < 0.001). Before the administration of epinephrine, no ventricular tachyarrhythmias or seizures were found in either the control or the magnesium-deficient rats. The incidence of epinephrine-induced sustained ventricular tachycardia (VT) was higher in the magnesium-deficient rats (86%) than in the control rats (43%, P < 0.01). However, this VT did not result in sudden death. Seizures always preceded death in both the magnesium-deficient and control rats while the arrhythmias observed immediately before death were mainly bradyarrhythmias. The present study in an adult rat magnesium-deficient model revealed that magnesium deficiency enhances the susceptibility to epinephrine-induced ventricular tachyarrhythmias. | lld:pubmed |
pubmed-article:10328182 | pubmed:language | eng | lld:pubmed |
pubmed-article:10328182 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10328182 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:10328182 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10328182 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10328182 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10328182 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:10328182 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:10328182 | pubmed:issn | 0910-8327 | lld:pubmed |
pubmed-article:10328182 | pubmed:author | pubmed-author:NakamuraMM | lld:pubmed |
pubmed-article:10328182 | pubmed:author | pubmed-author:TomiyasuTT | lld:pubmed |
pubmed-article:10328182 | pubmed:author | pubmed-author:ChishakiAA | lld:pubmed |
pubmed-article:10328182 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:10328182 | pubmed:volume | 13 | lld:pubmed |
pubmed-article:10328182 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:10328182 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:10328182 | pubmed:pagination | 122-31 | lld:pubmed |
pubmed-article:10328182 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:10328182 | pubmed:year | 1998 | lld:pubmed |
pubmed-article:10328182 | pubmed:articleTitle | Magnesium deficiency in adult rats promotes the induction of ventricular tachycardia by the administration of epinephrine. | lld:pubmed |
pubmed-article:10328182 | pubmed:affiliation | The Graduate School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan. | lld:pubmed |
pubmed-article:10328182 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:10328182 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:10328182 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |