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pubmed-article:10321849pubmed:abstractTextBleeding due to coagulopathy is a frequent complication of severe sepsis, especially in burn patients. The primary treatment is aimed at the underlying cause but additional supportive measures, consisting mainly of coagulation factor replacement, are frequently necessary. We describe the salutary effect of continuous veno-venous haemofiltration (CVVH) with predilution on diffuse haemorrhage in a patient with severe septic shock and renal failure. The diffuse haemorrhage was initially treated with replacement of coagulation factors. Prothrombin time and partial thromboplastin time became normal while diffuse bleeding continued and the thrombelastogram showed evidence of fibrinolysis. A short period of CVVH lead to the cessation of bleeding which was reflected by a normal thrombelastogram.lld:pubmed
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pubmed-article:10321849pubmed:authorpubmed-author:OppenheimAAlld:pubmed
pubmed-article:10321849pubmed:authorpubmed-author:SprungC LCLlld:pubmed
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pubmed-article:10321849pubmed:authorpubmed-author:PerouanskyMMlld:pubmed
pubmed-article:10321849pubmed:authorpubmed-author:EidelmanL ALAlld:pubmed
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pubmed-article:10321849pubmed:volume40lld:pubmed
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pubmed-article:10321849pubmed:pagination53-6lld:pubmed
pubmed-article:10321849pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:10321849pubmed:year1999lld:pubmed
pubmed-article:10321849pubmed:articleTitleEffect of haemofiltration on pathological fibrinolysis due to severe sepsis: a case report.lld:pubmed
pubmed-article:10321849pubmed:affiliationDepartment of Anesthesiology and Critical Care Medicine, Hadassah University Medical Center, The Hebrew University School of Medicine, Jerusalem, Israel.lld:pubmed
pubmed-article:10321849pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10321849pubmed:publicationTypeCase Reportslld:pubmed