Linked Life Data

10229581

Source:http://linkedlifedata.com/resource/pubmed/id/10229581

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:10229581rdf:typepubmed:Citationlld:pubmed
pubmed-article:10229581lifeskim:mentionsumls-concept:C1179435lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C0887887lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C1325417lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C0245603lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C0528008lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C0439659lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C1519068lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C1705248lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C0205214lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C1548799lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C1524073lld:lifeskim
pubmed-article:10229581lifeskim:mentionsumls-concept:C0449432lld:lifeskim
pubmed-article:10229581pubmed:issue6lld:pubmed
pubmed-article:10229581pubmed:dateCreated1999-7-16lld:pubmed
pubmed-article:10229581pubmed:abstractTextEukaryotic vesicular transport requires the recognition of membranes through specific protein complexes. The heterotetrameric adaptor protein complexes 1, 2, and 3 (AP1/2/3) are composed of two large, one small, and one medium adaptin subunit. We isolated and characterized the cDNA for Arabidopsis gamma-adaptin and performed a phylogenetic analysis of all adaptin subunits (proteins) in the context of all known homologous proteins. This analysis revealed (i) that the large subunits of AP1/2/3 are homologous and (ii) two subunits of the heptameric coatomer I (COPI) complex belong to this gene family. In addition, all small subunits and the aminoterminal domain of the medium subunits of the heterotetramers are homologous to each other; this also holds for two corresponding subunits of the COPI complex. AP1/2/3 and a substructure (heterotetrameric, F-COPI subcomplex) of the heptameric COPI had a common ancestral complex (called pre-F-COPI). Since all large and all small/medium subunits share sequence similarity, the ancestor of this complex is inferred to have been a heterodimer composed of one large and one small subunit. The situation encountered today is the result of successive rounds of coordinated gene duplications of both the large and the small/medium subunits, with F-COPI being the first that separated from the ancestral pre-F-COPI.lld:pubmed
pubmed-article:10229581pubmed:languageenglld:pubmed
pubmed-article:10229581pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10229581pubmed:citationSubsetIMlld:pubmed
pubmed-article:10229581pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10229581pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10229581pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10229581pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10229581pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10229581pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:10229581pubmed:statusMEDLINElld:pubmed
pubmed-article:10229581pubmed:monthJunlld:pubmed
pubmed-article:10229581pubmed:issn0022-2844lld:pubmed
pubmed-article:10229581pubmed:authorpubmed-author:BrinkmannHHlld:pubmed
pubmed-article:10229581pubmed:authorpubmed-author:MendelR RRRlld:pubmed
pubmed-article:10229581pubmed:authorpubmed-author:SchledzewskiK...lld:pubmed
pubmed-article:10229581pubmed:issnTypePrintlld:pubmed
pubmed-article:10229581pubmed:volume48lld:pubmed
pubmed-article:10229581pubmed:ownerNLMlld:pubmed
pubmed-article:10229581pubmed:authorsCompleteYlld:pubmed
pubmed-article:10229581pubmed:pagination770-8lld:pubmed
pubmed-article:10229581pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:meshHeadingpubmed-meshheading:10229581...lld:pubmed
pubmed-article:10229581pubmed:year1999lld:pubmed
pubmed-article:10229581pubmed:articleTitlePhylogenetic analysis of components of the eukaryotic vesicle transport system reveals a common origin of adaptor protein complexes 1, 2, and 3 and the F subcomplex of the coatomer COPI.lld:pubmed
pubmed-article:10229581pubmed:affiliationBotanical Institute, Technical University of Braunschweig, Humboldtstrasse 1, 38106 Braunschweig, Germany.lld:pubmed
pubmed-article:10229581pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:10229581pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:839001entrezgene:pubmedpubmed-article:10229581lld:entrezgene
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:10229581lld:pubmed