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pubmed-article:10217830pubmed:abstractTextNeuronotropic viruses induce apoptosis in neurons, and Bcl-2-related anti-apoptotic proteins and caspase inhibitors decrease mortality from acute viral encephalitis. Infected neurons develop cytoplasmic blebbing characteristic of apoptosis, but a paucity of apoptotic nuclear changes potentially indicates unique aspects of virus-induced neuronal apoptosis that remain to be discovered.lld:pubmed
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pubmed-article:10217830pubmed:articleTitlePerspective: virus infections and the death of neurons.lld:pubmed
pubmed-article:10217830pubmed:affiliationDept of Molecular Microbiology and Immunology, Johns Hopkins University School of Hygiene and Public Health, 615 N. Wolfe St, Baltimore, MD 21205, USA.dgriffin@jhsph.edulld:pubmed
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