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pubmed-article:10209569pubmed:abstractTextThe physiological effects of oestrogens on bone in men were largely unanticipated until recently, when oestrogen deficiency in males with aromatase deficiency and oestrogen resistance was found to cause osteoporosis and delayed fusion of epiphyses despite sufficient serum testosterone. This raises the possibility that in normal men oestrogens rather than androgens are of physiological importance in bone maturation. In the present study, we examined the association of serum oestradiol (E2) compared to that of free testosterone (FT) with bone mineral density (BMD) in normal men. The effect of oestrogen receptor (ER) gene polymorphism on BMD in men was also addressed.lld:pubmed
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pubmed-article:10209569pubmed:articleTitleSerum oestradiol and oestrogen-receptor gene polymorphism are associated with bone mineral density independently of serum testosterone in normal males.lld:pubmed
pubmed-article:10209569pubmed:affiliationDepartment of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.lld:pubmed
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