| pubmed-article:10200256 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10200256 | lifeskim:mentions | umls-concept:C0162571 | lld:lifeskim |
| pubmed-article:10200256 | lifeskim:mentions | umls-concept:C0524637 | lld:lifeskim |
| pubmed-article:10200256 | lifeskim:mentions | umls-concept:C0080347 | lld:lifeskim |
| pubmed-article:10200256 | lifeskim:mentions | umls-concept:C0012935 | lld:lifeskim |
| pubmed-article:10200256 | lifeskim:mentions | umls-concept:C0058594 | lld:lifeskim |
| pubmed-article:10200256 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:10200256 | pubmed:dateCreated | 1999-5-17 | lld:pubmed |
| pubmed-article:10200256 | pubmed:abstractText | Bacteriophage T7 DNA primase recognizes 5'-GTC-3' in single-stranded DNA. The primase contains a single Cys4 zinc-binding motif that is essential for recognition. Biochemical and mutagenic analyses suggest that the Cys4 motif contacts cytosine of 5'-GTC-3' and may also contribute to thymine recognition. Residues His33 and Asp31 are critical for these interactions. Biochemical analysis also reveals that T7 primase selectively binds CTP in the absence of DNA. We propose that bound CTP selects the remaining base G, of 5'-GTC-3', by base pairing. Our deduced mechanism for recognition of ssDNA by Cys4 motifs bears little resemblance to the recognition of trinucleotides of double-stranded DNA by Cys2His2 zinc fingers. | lld:pubmed |
| pubmed-article:10200256 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10200256 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10200256 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10200256 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:10200256 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:10200256 | pubmed:author | pubmed-author:RichardsonC... | lld:pubmed |
| pubmed-article:10200256 | pubmed:author | pubmed-author:KusakabeTT | lld:pubmed |
| pubmed-article:10200256 | pubmed:author | pubmed-author:HybertsS GSG | lld:pubmed |
| pubmed-article:10200256 | pubmed:author | pubmed-author:KaleS MSM | lld:pubmed |
| pubmed-article:10200256 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10200256 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:10200256 | pubmed:volume | 96 | lld:pubmed |
| pubmed-article:10200256 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10200256 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10200256 | pubmed:pagination | 4295-300 | lld:pubmed |
| pubmed-article:10200256 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:meshHeading | pubmed-meshheading:10200256... | lld:pubmed |
| pubmed-article:10200256 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10200256 | pubmed:articleTitle | The Cys4 zinc finger of bacteriophage T7 primase in sequence-specific single-stranded DNA recognition. | lld:pubmed |
| pubmed-article:10200256 | pubmed:affiliation | Department of Biological Chemistry and Molecular Pharmacology, Harvard University Medical School, Boston, MA 02115, USA. | lld:pubmed |
| pubmed-article:10200256 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10200256 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10200256 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
