| pubmed-article:10099999 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10099999 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:10099999 | lifeskim:mentions | umls-concept:C0026088 | lld:lifeskim |
| pubmed-article:10099999 | lifeskim:mentions | umls-concept:C0033568 | lld:lifeskim |
| pubmed-article:10099999 | lifeskim:mentions | umls-concept:C0085174 | lld:lifeskim |
| pubmed-article:10099999 | lifeskim:mentions | umls-concept:C0205195 | lld:lifeskim |
| pubmed-article:10099999 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:10099999 | pubmed:dateCreated | 1999-5-26 | lld:pubmed |
| pubmed-article:10099999 | pubmed:abstractText | In this two centre study, the efficacy of 200 mg mifepristone orally followed 48 h later by 0.4 mg misoprostol orally for menstrual regulation was investigated. The dose of mifepristone was taken the day before the expected day of menstruation. Each volunteer was planned to participate for up to 6 months. A plasma beta human chorionic gonadotrophin (HCG) was measured on the day of mifepristone intake. The study was disrupted prematurely due to low efficacy. In 125 treatment cycles the overall pregnancy rate was 17.6% (22 pregnancies) and the rate of continuing pregnancies (failure) was 4.0%. Eight women discontinued the study due to bleeding irregularities which were seen in 15 cycles (12%). These effects on bleeding pattern made the timing of treatment day difficult. Late luteal phase treatment with a combination of mifepristone and misoprostol is not adequately effective for menstrual regulation. | lld:pubmed |
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| pubmed-article:10099999 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10099999 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10099999 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10099999 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10099999 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10099999 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10099999 | pubmed:issn | 0268-1161 | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:ChenJ KJK | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:BygdemanMM | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:YangP JPJ | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:SongSS | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:SwahnM LML | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:Gemzell-Danie... | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:QianM LML | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:YangQ YQY | lld:pubmed |
| pubmed-article:10099999 | pubmed:author | pubmed-author:ChangW FWF | lld:pubmed |
| pubmed-article:10099999 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10099999 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:10099999 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10099999 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10099999 | pubmed:pagination | 485-8 | lld:pubmed |
| pubmed-article:10099999 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10099999 | pubmed:otherAbstract | PIP: A 2-center study was undertaken to examine the efficacy, safety and acceptability of a once-a-month administration of a combination of 200 mg mifepristone and 0.4 mg misoprostol for menstrual regulation in the late luteal phase. About 24 women from Shanghai and 8 from Stockholm were administered 200 mg mifepristone taken orally before or on the day of menstruation, followed by 0.4 mg misoprostol taken orally after 48 hours. Urine samples were collected during 3 days before to 4 days after ovulation for an analysis of luteinizing hormone. In addition, a plasma beta human chorionic gonadotrophin was measured immediately before intake of mifepristone. Volunteers were to participate for 6 months, but the study was disrupted prematurely due to low efficacy. In 125 treatment cycles, the total pregnancy rate was 17.6% (22 pregnancies) and the failure pregnancy rate was 4.0%. Discontinuation of the study among 8 women was due to bleeding disturbances seen in 15 cycles (12%). In conclusion, late luteal phase treatment with a combination of mifepristone and misoprostol was not effective enough to be used for menstrual regulation. | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:meshHeading | pubmed-meshheading:10099999... | lld:pubmed |
| pubmed-article:10099999 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10099999 | pubmed:articleTitle | Once-a-month treatment with a combination of mifepristone and the prostaglandin analogue misoprostol. | lld:pubmed |
| pubmed-article:10099999 | pubmed:affiliation | Department of Obstetrics and Gynecology, Huddinge University Hospital, Sweden. | lld:pubmed |
| pubmed-article:10099999 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10099999 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:10099999 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10099999 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10099999 | lld:pubmed |
